Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925512 | 0.81 | CHRNB2 (0.44) | CYP3A4 | |
| SCHEMBL1925418 | 0.80 | ADRB2 (0.41) | MAPTNPSR1TSHRLMNATDP1 | |
| SCHEMBL15704762 | 0.78 | SIGMAR1 (0.42) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL4538917 | 0.78 | HTR3E (0.39) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL14889007 | 0.78 | KMT2A (0.35) | MAPTNPSR1NPC1RAB9AHPGD | |
| SCHEMBL5802739 | 0.74 | NPC1 (0.41) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14889037 | 0.71 | SIRT6 (0.47) | ADRB1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1927670 | 0.71 | MGLL (0.37) | GSK3AGSK3B | |
| SCHEMBL17766629 | 0.70 | ALDH1A1 (0.44) | MAPTNPSR1NPC1RAB9AHPGD | |
| SCHEMBL10964131 | 0.70 | SIGMAR1 (0.42) | SIGMAR1HTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220625-A | A kind of synthetic method of pirenzepine hydrochloride key intermediate | 常州大学 | 2016-12-14 | — | — | CN | claimed |
| CN-101052640-A | Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors | APPLIED RESEARCH SYSTEMS (AN) | 2007-10-10 | — | — | CN | claimed |
| CN-118290346-A | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-112703184-B | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-06-11 | — | — | CN | disclosed |
| US-11744142-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-29 | — | — | US | disclosed |
| CN-115197225-B | Five-membered heterocyclic quinazolinone compound and preparation method thereof | 贵州大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-110396116-B | [ N, O ] bidentate nickel and palladium complex of ketone-imidazoline-2-imine ligand, and preparation method and application thereof | 东华大学 | 2020-07-28 | — | — | CN | disclosed |
| US-20190051845-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-02-14 | — | — | US | disclosed |
| CN-108349940-A | Bruton's tyrosine kinase inhibitor | 淄博百极常生制药有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107074769-A | Compositions and methods for treating proliferative disorders | 艾科尔公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106220625-A | A kind of synthetic method of pirenzepine hydrochloride key intermediate | 常州大学 | 2016-12-14 | — | — | CN | disclosed |
| US-20130303776-A1 | LUMINESCENT MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT, WAVELENGTH-CONVERTING LIGHT-EMITTING ELEMENT, LIGHT-CONVERTING LIGHT-EMITTING ELEMENT, ORGANIC LASER DIODE LIGHT-EMITTING ELEMENT, DYE LASER, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAME | SHARP KABUSHIKI KAISHA (JP) | 2013-11-14 | — | — | US | disclosed |
| US-20130303777-A1 | LUMINESCENT MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT, WAVELENGTH-CONVERTING LIGHT-EMITTING ELEMENT, LIGHT-CONVERTING LIGHT-EMITTING ELEMENT, ORGANIC LASER DIODE LIGHT-EMITTING ELEMENT, DYE LASER, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAME | SHARP KABUSHIKI KAISHA (JP) | 2013-11-14 | — | — | US | disclosed |
| US-20130284210-A1 | SOLID FORMULATIONS, THEIR PREPARATION AND USE | BASF SE (DE) | 2013-10-31 | — | — | US | disclosed |
| CN-101052640-B | Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors | LABORATROIRES SERONO SA | 2011-05-11 | — | — | CN | disclosed |
| CN-101925606-A | Compounds comprising a cyclobutoxy group | UCB PHARMA SA | 2010-12-22 | — | — | CN | disclosed |
| CN-101052640-A | Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors | APPLIED RESEARCH SYSTEMS (AN) | 2007-10-10 | — | — | CN | disclosed |
| EP-1692130-A2 | PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS | University Court of The University of Glasgow (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6960601-B2 | Preparation and use of imidazole derivatives for treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |
| WO-2005054241-A2 | PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11744142-B2 | Organic electroluminescent materials and devices | TLL1, TLL2, ALPL | SIGMAR1 2941/4885HTR3E 3028/4885HTR3B 3798/4885 |
| US-20190051845-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | TLL1, TLL2, ALPL | SIGMAR1 2941/4885HTR3E 3028/4885HTR3B 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.