Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245740 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAGAATAS1R3TAS1R1 | |
| SCHEMBL6244352 | 0.78 | TAS1R3 (0.43) | ALDH1A1GAATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5151365 | 0.78 | ABCC9 (0.44) | LMNATAS1R3TAS1R1TAS1R2CYP17A1 | |
| SCHEMBL5731619 | 0.77 | POLB (0.54) | ALDH1A1GAARAB9ANPC1CASP3 | |
| SCHEMBL6240779 | 0.76 | ABCC9 (0.43) | LMNATAS1R3TAS1R1TAS1R2CYP17A1 | |
| SCHEMBL5154485 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1LMNANPY1RNPY2RRAB9A | |
| SCHEMBL628865 | 0.74 | MAPT (0.46) | ALDH1A1LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30587156 | 0.74 | MAPT (0.46) | ALDH1A1LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6242304 | 0.73 | KMT2A (0.47) | ALDH1A1LMNAGAANPY1RNPY2R | |
| SCHEMBL15688622 | 0.73 | CNR1 (0.33) | ALDH1A1LMNAGAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975149-B1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-7700808-B2 | 1-3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1975149-A1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1538138-A1 | SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | HCN1, CNPY2, CLIC1 | ALDH1A1 696/4885LMNA 529/4885GAA 4745/4885 |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | GCN1, L3MBTL3, L3MBTL4 | ALDH1A1 1987/4885LMNA 3354/4885GAA 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.