Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222841 | 0.82 | ALDH1A1 (0.39) | ALDH1A1OPRM1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL7640011 | 0.82 | MAPT (0.47) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL124147 | 0.82 | MAPT (0.47) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL6051256 | 0.79 | LMNA (0.44) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL342177 | 0.76 | MAPT (0.43) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL28401715 | 0.76 | DRD2 (0.39) | KMT2AALDH1A1MEN1 | |
| SCHEMBL694567 | 0.76 | LMNA (0.48) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL28401713 | 0.70 | LMNA (0.42) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL17584752 | 0.70 | ALDH1A1 (0.41) | MAPTKDM4ERECQLTDP1KMT2A | |
| SCHEMBL29205863 | 0.69 | MAPT (0.46) | MAPTKDM4ERECQLTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148647-A1 | Combinations of phenylsulfonylurea herbicides and safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-07-06 | — | — | US | claimed |
| US-20040157737-A1 | For protecting crop plants from phytotoxic side effects of herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-08-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148647-A1 | Combinations of phenylsulfonylurea herbicides and safeners | QSOX1, CYP2W1, SULT2A1 | MAPT 4802/4885KDM4E 2765/4885RECQL 1156/4885 |
| US-20040157737-A1 | For protecting crop plants from phytotoxic side effects of herbicides | GSTO1, CYP1A1, HAO2 | MAPT 4392/4885KDM4E 2788/4885RECQL 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.