Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065290 | 0.95 | DUT (0.30) | — | |
| SCHEMBL6065097 | 0.71 | PKM (0.45) | LMNA | |
| SCHEMBL6065131 | 0.70 | LMNA (0.40) | LMNA | |
| SCHEMBL6066190 | 0.70 | SMN1; SMN2 (0.35) | LMNA | |
| SCHEMBL6065740 | 0.68 | F2 (0.41) | LMNA | |
| SCHEMBL6065016 | 0.67 | KMT2A (0.33) | LMNA | |
| SCHEMBL6065771 | 0.65 | LMNA (0.35) | LMNA | |
| SCHEMBL6557418 | 0.62 | HSD17B10 (0.36) | LMNA | |
| SCHEMBL6558372 | 0.61 | POLB (0.43) | LMNA | |
| SCHEMBL6557414 | 0.61 | MTNR1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |