SCHEMBL607633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL608266	0.84	NOX4 (0.61)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL29391103	0.84	NOX4 (0.61)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL4093950	0.82	NOX4 (0.59)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL608754	0.82	NOX4 (0.61)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL29389796	0.81	NOX4 (0.57)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL607105	0.81	NOX4 (0.57)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL29388214	0.78	AKR1C3 (0.55)	ALDH1A1MAPTKDM4CPPARAMEN1
	SCHEMBL4095004	0.78	KDM4C (0.56)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL4098010	0.78	NOX4 (0.50)	NOX4ALDH1A1EGFRMAPTRGS12
	SCHEMBL12862660	0.77	ALDH1A1 (0.57)	NOX4ALDH1A1EGFRMAPTRGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.