Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391103 | 1.00 | NOX4 (0.61) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL4089718 | 0.86 | CA1 (0.53) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL607633 | 0.84 | NOX4 (0.61) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL4093950 | 0.82 | NOX4 (0.59) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL608754 | 0.82 | NOX4 (0.61) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL607105 | 0.81 | NOX4 (0.57) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL29389796 | 0.81 | NOX4 (0.57) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL29391568 | 0.79 | KDM4C (0.53) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL610065 | 0.79 | KDM4C (0.53) | NOX4EGFRALDH1A1MAPTRGS12 | |
| SCHEMBL610123 | 0.78 | SYK (0.58) | NOX4EGFRALDH1A1MAPTRGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3902536-B1 | COMPOSITIONS COMPRISING 5-BENZYLAMINOSALICYLIC ACID COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IN A COMPANION ANIMAL | GNT PHARMA CO LTD (KR) | 2025-09-03 | — | — | EP | claimed |
| EP-4456890-A2 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS | GNT Pharma Co., Ltd (KR) | 2024-11-06 | — | — | EP | claimed |
| WO-2023156808-A2 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS | GNT PHARMA CO., LTD. (KR) | 2023-08-24 | — | — | WO | claimed |
| US-20230233503-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS | GNT PHARMA CO., LTD. (KR) | 2023-07-27 | — | — | US | claimed |
| US-20220249343-A1 | COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF | GNT PHARMA CO., LTD. (KR) | 2022-08-11 | — | — | US | claimed |
| US-20220241231-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | GNT PHARMA CO., LTD. (KR) | 2022-08-04 | — | — | US | claimed |
| CN-114096227-A | Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof | 吉恩特药业株式会社 | 2022-02-25 | — | — | CN | claimed |
| CN-113710242-A | Compositions and methods for treating neurodegenerative disorders | 吉恩特药业株式会社 | 2021-11-26 | — | — | CN | claimed |
| EP-3902536-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | GNT Pharma Co., Ltd (KR) | 2021-11-03 | — | — | EP | claimed |
| US-20200206172-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | GNT PHARMA CO., LTD. (KR) | 2020-07-02 | — | — | US | claimed |
| WO-2020136441-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | GNT PHARMA CO., LTD. (KR) | 2020-07-02 | — | — | WO | claimed |
| US-20130316988-A1 | Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2013-11-28 | — | — | US | claimed |
| US-8455470-B2 | Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases | NEUROTECH PHARMACEUTICALS CO., LTD (KR) | 2013-06-04 | — | — | US | claimed |
| US-20120040939-A1 | MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2012-02-16 | — | — | US | claimed |
| CN-102316863-A | The medical usage of 5-benzylamino salicyclic acid derivatives or its salt | NEUROTECH PHARMACEUTICALS CO L | 2012-01-11 | — | — | CN | claimed |
| US-20090281181-A1 | Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases | GNT PHARMA CO., LTD. (KR) | 2009-11-12 | — | — | US | claimed |
| US-20090149542-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2009-06-11 | — | — | US | claimed |
| EP-2004164-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES | Neurotech Co., Ltd. (KR) | 2008-12-24 | — | — | EP | claimed |
| US-20070298129-A1 | Compounds and compositions for treating neuronal death or neurological dysfunction | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2007-12-27 | — | — | US | claimed |
| WO-2007119973-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES | NEUROTECH CO., LTD. (KR) | 2007-10-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149542-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION | BCL2, BAX, SMN1; SMN2 | NOX4 2363/4885EGFR 2671/4885ALDH1A1 1961/4885 |
| US-20230233503-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS | HAO2, ACOX1, HAO1 | NOX4 195/4885EGFR 3946/4885ALDH1A1 309/4885 |
| US-20220241231-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | PRNP, PSEN1, GRIK5 | NOX4 4612/4885EGFR 3139/4885ALDH1A1 859/4885 |
| US-20070298129-A1 | Compounds and compositions for treating neuronal death or neurological dysfunction | BCL2, BAX, SMN1; SMN2 | NOX4 2363/4885EGFR 2671/4885ALDH1A1 1961/4885 |
| US-20120040939-A1 | MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT | HTR5A, HTR6, MC5R | NOX4 1222/4885EGFR 3070/4885ALDH1A1 133/4885 |
| US-20090281181-A1 | Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases | ALOX12, ALOX15, ALOX15B | NOX4 1202/4885EGFR 2155/4885ALDH1A1 446/4885 |
| US-20130316988-A1 | Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases | ALOX12, ALOX15, ALOX15B | NOX4 1202/4885EGFR 2155/4885ALDH1A1 446/4885 |
| US-20220249343-A1 | COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF | ALOX5, ALOX15, IL5 | NOX4 1921/4885EGFR 4006/4885ALDH1A1 93/4885 |
| US-20200206172-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | PRNP, PSEN1, GRIK5 | NOX4 4612/4885EGFR 3139/4885ALDH1A1 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.