SCHEMBL607105

SCHEMBL607105

O=C(O)c1cc(NCCc2ccccc2[N+](=O)[O-])ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX4 Q9NPH5 2/20 0.57
CDK2 P24941 6/20 0.49
ALDH3A1 P30838 1/20 0.49
ALDH1A1 P00352 5/20 0.48
MAPT P10636 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
EGFR P00533 2/20 0.48
RGS12 O14924 1/20 0.48
LCK P06239 1/20 0.48
CAMKK2 Q96RR4 1/20 0.48
KDM4C Q9H3R0 2/20 0.46
KMT2A Q03164 2/20 0.45
MAPK1 P28482 2/20 0.45
MEN1 O00255 1/20 0.45
HTT P42858 1/20 0.45
PPARA Q07869 1/20 0.44
STING1 Q86WV6 1/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389796 1.00 NOX4 (0.57) NOX4CDK2ALDH3A1ALDH1A1MAPT
SCHEMBL5316377 0.81 POLB (0.53) NOX4ALDH1A1MAPTTDP1KMT2A
SCHEMBL29391103 0.81 NOX4 (0.61) NOX4ALDH1A1MAPTTDP1EGFR
SCHEMBL607633 0.81 NOX4 (0.61) NOX4ALDH1A1MAPTTDP1EGFR
SCHEMBL608266 0.81 NOX4 (0.61) NOX4ALDH1A1MAPTTDP1EGFR
SCHEMBL609284 0.79 MAPT (0.56) NOX4CDK2ALDH1A1MAPTTDP1
SCHEMBL29390925 0.79 MAPT (0.56) NOX4CDK2ALDH1A1MAPTTDP1
SCHEMBL4093950 0.79 NOX4 (0.59) NOX4CDK2ALDH1A1MAPTTDP1
SCHEMBL608754 0.79 NOX4 (0.61) NOX4ALDH1A1MAPTTDP1EGFR
SCHEMBL7095935 0.78 ALDH1A1 (0.63) ALDH3A1ALDH1A1MAPTTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902536-B1 COMPOSITIONS COMPRISING 5-BENZYLAMINOSALICYLIC ACID COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IN A COMPANION ANIMAL GNT PHARMA CO LTD (KR) 2025-09-03 EP claimed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 WO claimed
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-07-27 US claimed
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF GNT PHARMA CO., LTD. (KR) 2022-08-11 US claimed
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2022-08-04 US claimed
EP-3998058-A1 COSMETIC COMPOSITION COMPRISING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE AND LOCAL ADMINISTRATION METHOD THEREOF GNT Pharma Co., Ltd (KR) 2022-05-18 EP claimed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 CN claimed
CN-113710242-A Compositions and methods for treating neurodegenerative disorders 吉恩特药业株式会社 2021-11-26 CN claimed
EP-3902536-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT Pharma Co., Ltd (KR) 2021-11-03 EP claimed
WO-2020136441-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2020-07-02 WO claimed
EP-2004164-B1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING INFLAMMATORY DISEASES NEUROTECH PHARMACEUTICALS CO LTD (KR) 2018-08-08 EP claimed
US-20130316988-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2013-11-28 US claimed
CN-103211824-A Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases NEUROTECH PHARMACEUTICALS CO LTD 2013-07-24 CN claimed
US-8455470-B2 Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases NEUROTECH PHARMACEUTICALS CO., LTD (KR) 2013-06-04 US claimed
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2012-02-16 US claimed
CN-102316863-A The medical usage of 5-benzylamino salicyclic acid derivatives or its salt NEUROTECH PHARMACEUTICALS CO L 2012-01-11 CN claimed
US-20090281181-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases GNT PHARMA CO., LTD. (KR) 2009-11-12 US claimed
CN-101426484-A Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases NEUROTECH CO LTD (KR) 2009-05-06 CN claimed
EP-2004164-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES Neurotech Co., Ltd. (KR) 2008-12-24 EP claimed
WO-2007119973-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES NEUROTECH CO., LTD. (KR) 2007-10-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS HAO2, ACOX1, HAO1 NOX4 195/4885CDK2 4386/4885ALDH3A1 612/4885
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS PRNP, PSEN1, GRIK5 NOX4 4612/4885CDK2 3143/4885ALDH3A1 1822/4885
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT HTR5A, HTR6, MC5R NOX4 1222/4885CDK2 4721/4885ALDH3A1 191/4885
US-20090281181-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B NOX4 1202/4885CDK2 1682/4885ALDH3A1 1685/4885
US-20130316988-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B NOX4 1202/4885CDK2 1682/4885ALDH3A1 1685/4885
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF ALOX5, ALOX15, IL5 NOX4 1921/4885CDK2 4115/4885ALDH3A1 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.