Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609342 | 1.00 | LMNA (0.36) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL16592821 | 0.78 | LMNA (0.46) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL16592822 | 0.78 | LMNA (0.46) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL11495779 | 0.74 | LMNA (0.36) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL11495776 | 0.74 | LMNA (0.36) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL10995648 | 0.74 | HSD17B10 (0.41) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL10995652 | 0.74 | HSD17B10 (0.41) | LMNAKDM4EHTTSMN1; SMN2USP2 | |
| SCHEMBL4800682 | 0.72 | L3MBTL1 (0.47) | LMNAKDM4ESMN1; SMN2USP2ALOX15 | |
| SCHEMBL3432777 | 0.69 | ALDH1A1 (0.44) | HTTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL3432776 | 0.69 | ALDH1A1 (0.44) | HTTSMN1; SMN2NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052959-B1 | PRODUCTION OF PURINE DERIVATIVES AND INTERMEDIATES THEREFOR | Takeda Chemical Industries, Ltd. (JP) | 1986-01-29 | — | — | EP | claimed |
| EP-0052959-A1 | Production of purine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | claimed |
| JP-58032867-A | — | — | None | — | — | JP | disclosed |
| EP-3224262-B1 | NEW METAL N-AMINOGUANIDINATE COMPLEXES FOR USE IN THIN FILM FABRICATION AND CATALYSIS | UMICORE AG & CO KG (DE) | 2020-08-26 | — | — | EP | disclosed |
| US-10093687-B2 | Metal N-aminoguanidinate complexes for use in thin film fabrication and catalysis | UMICORE AG & CO. KG (DE) | 2018-10-09 | — | — | US | disclosed |
| EP-3224262-A1 | NEW METAL N-AMINOGUANIDINATE COMPLEXES FOR USE IN THIN FILM FABRICATION AND CATALYSIS | Umicore AG & Co. KG (DE) | 2017-10-04 | — | — | EP | disclosed |
| US-20170260213-A1 | NEW METAL N-AMINOGUANIDINATE COMPLEXES FOR USE IN THIN FILM FABRICATION AND CATALYSIS | UMICORE AG & CO. KG (DE) | 2017-09-14 | — | — | US | disclosed |
| WO-2016083471-A1 | NEW METAL N-AMINOGUANIDINATE COMPLEXES FOR USE IN THIN FILM FABRICATION AND CATALYSIS | UMICORE AG & CO. KG (DE) | 2016-06-02 | — | — | WO | disclosed |
| EP-3026055-A1 | New metal N-aminoguanidinate complexes for use in thin film fabrication and catalysis | Umicore AG & Co. KG (DE) | 2016-06-01 | — | — | EP | disclosed |
| US-20120130058-A1 | REDUCTION OF 5-(ARYL-DIAZENYL)-4,6-DIHALO-PYRIMIDINE | QUITTMANN WILHELM (CH) | 2012-05-24 | — | — | US | disclosed |
| US-8114996-B2 | Reduction of 5-(aryl-diazenyl)-4,6-dihalo-pyrimidine | LONZA AG (CH) | 2012-02-14 | — | — | US | disclosed |
| US-5516905-A | ENZYME INHIBITORS OF DNA POLYMERASE FOR BACTERICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1996006614-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-03-07 | — | — | WO | disclosed |
| EP-0052959-B1 | PRODUCTION OF PURINE DERIVATIVES AND INTERMEDIATES THEREFOR | Takeda Chemical Industries, Ltd. (JP) | 1986-01-29 | — | — | EP | disclosed |
| EP-0101273-A2 | Production of biological products using resting cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4423219-A | 6-/2-CHLORO-6-FLUOROBENZYL/AMINO-4-METHYLAMINO-5 -PHENYLAZOPYRIMIDINE, ANTIPROTOZOA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| US-4423219-A | 6-/2-CHLORO-6-FLUOROBENZYL/AMINO-4-METHYLAMINO-5 -PHENYLAZOPYRIMIDINE, ANTIPROTOZOA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| JP-S5832867-A | NOVEL ARYLAZOPYRIMIDINE COMPOUND | TAKEDA CHEM IND LTD | 1983-02-25 | — | — | JP | disclosed |
| EP-0052959-A1 | Production of purine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |
| EP-0052959-A1 | Production of purine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260213-A1 | NEW METAL N-AMINOGUANIDINATE COMPLEXES FOR USE IN THIN FILM FABRICATION AND CATALYSIS | GNMT, NNMT, AOX1 | LMNA 2410/4885KDM4E 1241/4885HTT 3905/4885 |
| US-20120130058-A1 | REDUCTION OF 5-(ARYL-DIAZENYL)-4,6-DIHALO-PYRIMIDINE | PDXK, KHK, GCK | LMNA 4657/4885KDM4E 2059/4885HTT 774/4885 |
| US-10093687-B2 | Metal N-aminoguanidinate complexes for use in thin film fabrication and catalysis | AOC1, AMD1, AOC2 | LMNA 2336/4885KDM4E 922/4885HTT 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.