SCHEMBL6130639

SCHEMBL6130639

Cc1ccc(S(=O)(=O)NCCN(C)C)cc1

nearest known ligand 0.81

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.81
CA2 P00918 1/20 0.81
CA9 Q16790 1/20 0.81
ALOX15 P16050 1/20 0.79
TSHR P16473 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73
ALDH1A1 P00352 11/20 0.71
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
HTT P42858 2/20 0.56
LMNA P02545 1/20 0.55
HPGD P15428 1/20 0.55
GAA P10253 1/20 0.54
SIGMAR1 Q99720 1/20 0.53
GBA1 P04062 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18553819 0.90 CA12 (1.00) CA12CA2CA9ALOX15TSHR
SCHEMBL12629636 0.89 ALDH1A1 (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL1348425 0.86 TSHR (0.73) CA12CA2CA9ALOX15TSHR
SCHEMBL4581466 0.86 ALDH1A1 (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL6355304 0.86 ALDH1A1 (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL5567042 0.85 ALDH1A1 (0.75) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL19152453 0.84 TSHR (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL7028080 0.84 TSHR (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL3327488 0.84 TSHR (0.71) CA12CA2CA9ALOX15TSHR
SCHEMBL19563408 0.84 SIGMAR1 (0.71) CA12CA2CA9ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490438-A Water-soluble quaternary ammonium salt antibacterial agent and preparation method thereof 苏州华道生物药业股份有限公司 2025-02-21 CN disclosed
US-20230321016-A1 COMBINATION THERAPY FOR TREATING CANCER GONGWIN BIOPHARM CO., LTD (TW) 2023-10-12 US disclosed
US-20230321016-A1 COMBINATION THERAPY FOR TREATING CANCER GONGWIN BIOPHARM CO., LTD (TW) 2023-10-12 US disclosed
US-11752118-B2 Method for treating melanoma GONGWIN BIOPHARM CO., LTD (TW) 2023-09-12 US disclosed
US-11752160-B2 Method for reducing fat by administering benzenesulfonamide compositions GONGWIN BIOPHARM CO., LTD (TW) 2023-09-12 US disclosed
US-11752118-B2 Method for treating melanoma GONGWIN BIOPHARM CO., LTD (TW) 2023-09-12 US disclosed
US-11752160-B2 Method for reducing fat by administering benzenesulfonamide compositions GONGWIN BIOPHARM CO., LTD (TW) 2023-09-12 US disclosed
US-20230062022-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS NUVATION BIO INC (US) 2023-03-02 US disclosed
WO-2022236256-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS NUVATION BIO INC. (US) 2022-11-10 WO disclosed
WO-2022236253-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS NUVATION BIO INC. (US) 2022-11-10 WO disclosed
US-20080113985-A1 Modulators of ATP-binding cassette transporters VERTEX PHARMACEUTICALS INCORPORATED 2008-05-15 US disclosed
US-20080019915-A1 including cystic fibrosis transmembrane conductance regulator (\"CFTR\"); N[6-(2-hydroxymethylphenyl-1yl)-5-methylpyrimidine][(4-methoxophenyl-1-yl)cyclopopyl]-amide; genetic disorders; respiratory system disorders, cystic fibrosis, hereditary emphysema and hemochromatosis, coagulation-fibrinolysis VERTEX PHARMACEUTICALS INCORPORATED 2008-01-24 US disclosed
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-09-27 US disclosed
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-09-27 US disclosed
US-20050064468-A1 concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports IBC ADVANCED TECHNOLOGIES, INC. 2005-03-24 US disclosed
EP-1453602-A4 COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES IBC ADVANCED TECH INC (US) 2005-01-12 EP disclosed
EP-1453602-A2 COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES IBC ADVANCED TECHNOLOGIES, INC. (US) 2004-09-08 EP disclosed
US-6774082-B2 COMPOSITION FOR USE IN THE SEPARATION OF PREFERENTIAL BIOPOLYMERS FROM SAMPLE IBC ADVANCED TECHNOLOGIES, INC. 2004-08-10 US disclosed
US-20030050458-A1 Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences IBC ADVANCED TECHNOLOGIES, INC. 2003-03-13 US disclosed
WO-2002092766-A2 COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES IBC ADVANCED TECHNOLOGIES, INC. (US) 2002-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11752160-B2 Method for reducing fat by administering benzenesulfonamide compositions LIPE, FABP4, LIPA CA12 4026/4885CA2 4175/4885CA9 1505/4885
US-20080019915-A1 including cystic fibrosis transmembrane conductance regulator (\"CFTR\"); N[6-(2-hydroxymethylphenyl-1yl)-5-methylpyrimidine][(4-methoxophenyl-1-yl)cyclopopyl]-amide; genetic disorders; respiratory system disorders, cystic fibrosis, hereditary emphysema and hemochromatosis, coagulation-fibrinolysis CFTR, ABCC8, ABCB1 CA12 4789/4885CA2 3603/4885CA9 4302/4885
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same CASR, CNR1, CNR2 CA12 1721/4885CA2 90/4885CA9 645/4885
US-20230062022-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS CDK4, CDK6, CDK8 CA12 3909/4885CA2 4392/4885CA9 3051/4885
US-20230321016-A1 COMBINATION THERAPY FOR TREATING CANCER TP53, MCL1, TOP2B CA12 239/4885CA2 989/4885CA9 76/4885
US-20030050458-A1 Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences NUDT1, ATIC, PNP CA12 2357/4885CA2 2291/4885CA9 2526/4885
US-20080113985-A1 Modulators of ATP-binding cassette transporters CFTR, ABCB1, ABCC2 CA12 4730/4885CA2 2789/4885CA9 4024/4885
US-11752118-B2 Method for treating melanoma TYR, MITF, BRAF CA12 376/4885CA2 1053/4885CA9 132/4885
US-20050064468-A1 concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports NUDT1, PCNA, NSUN2 CA12 2216/4885CA2 1909/4885CA9 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.