Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068155 | 0.90 | NPC1 (0.33) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL5053443 | 0.80 | NPC1 (0.32) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL6678233 | 0.80 | NPC1 (0.32) | NPC1RAB9ALMNAMAPK1CASP3 | |
| Hydrochloric Acid SCHEMBL11729554 | 0.79 | NPC1 (0.36) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL15067863 | 0.78 | SHBG (0.39) | SMN1; SMN2 | |
| SCHEMBL7850423 | 0.77 | NPC1 (0.33) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL780091 | 0.74 | NPC1 (0.43) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL15067135 | 0.72 | SHBG (0.38) | SMN1; SMN2 | |
| SCHEMBL23495993 | 0.71 | ALDH1A1 (0.30) | SMN1; SMN2 | |
| SCHEMBL5550734 | 0.69 | NPC1 (0.33) | NPC1RAB9ALMNAMAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797939-B1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2018-10-31 | — | — | EP | claimed |
| US-9108988-B2 | Method of purifying organic diphosphite compounds | BASF SE (DE) | 2015-08-18 | — | — | US | claimed |
| EP-2797939-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2014-11-05 | — | — | EP | claimed |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-08-29 | — | — | US | claimed |
| WO-2013098368-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-07-04 | — | — | WO | claimed |
| EP-3319951-B1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND FOR THE PREPARATION OF PRODUCTS DERIVED FROM SAME, PARTICULARLY FROM AMBROX | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| US-20180273458-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) | 2018-09-27 | — | — | US | disclosed |
| US-9108988-B2 | Method of purifying organic diphosphite compounds | BASF SE (DE) | 2015-08-18 | — | — | US | disclosed |
| EP-2797939-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2014-11-05 | — | — | EP | disclosed |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-08-29 | — | — | US | disclosed |
| WO-2013098368-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-07-04 | — | — | WO | disclosed |
| US-20020049355-A1 | Process for producing aldehyde | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-04-25 | — | — | US | disclosed |
| US-6291717-B1 | REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A RHODIUM COMPLEX CATALYST COMPRISING RHODIUM AND ORGANIC PHOSPHITE IN REACTION ZONE; SEPARATING CATALYST AND ALDEHYDE; RECYCLING CATALYST SOLUTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1066236-A4 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | RES FOUNDATION OF (US) | 2001-06-06 | — | — | EP | disclosed |
| EP-1066236-A1 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | The Research Foundation of State University of New York (US) | 2001-01-10 | — | — | EP | disclosed |
| EP-1008581-A1 | Process for producing aldehyde | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999050214-A1 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-07 | — | — | WO | disclosed |
| US-5962744-A | USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-05 | — | — | US | disclosed |
| US-5910600-A | Bisphosphite compound, process for its production and hydroformylation process employing the bisphosphite compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | ALOX12, ALOX15, ALOX5 | NPC1 2521/4885RAB9A 2892/4885LMNA 2087/4885 |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | DCTPP1, DCPS, PPIP5K2 | NPC1 1954/4885RAB9A 4044/4885LMNA 3922/4885 |
| US-20180273458-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | ALOX12, ALOX15, ALOX5 | NPC1 2521/4885RAB9A 2892/4885LMNA 2087/4885 |
| US-20020049355-A1 | Process for producing aldehyde | ALDH2, OGDH, HAO2 | NPC1 3305/4885RAB9A 1431/4885LMNA 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.