Sugi Predict

Sugi Predict / Compounds / SCHEMBL619005

SCHEMBL619005

SCHEMBL619005

O=COCCS(=O)(=O)c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.42
▸ TDP1 Q9NUW8 1/20 0.41
▸ ALDH1A1 P00352 4/20 0.41
▸ TSHR P16473 2/20 0.41
▸ NT5E P21589 1/20 0.41
▸ CA2 P00918 4/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ KMT2A Q03164 3/20 0.38
▸ HTT P42858 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ POLB P06746 2/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ MMP1 P03956 2/20 0.34
▸ MMP8 P22894 1/20 0.34
▸ MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605094 0.81 ALDH1A1 (0.41) LMNAALDH1A1CA2KMT2AHTT
SCHEMBL6750246 0.81 ALDH1A1 (0.47) LMNAALDH1A1CA2KMT2AMEN1
SCHEMBL64437 0.81 ALDH1A1 (0.60) LMNAALDH1A1SMN1; SMN2KMT2AHTT
SCHEMBL28052 0.81 PSIP1 (0.48) LMNAALDH1A1SMN1; SMN2KMT2AHTT
SCHEMBL10700258 0.81 LMNA (0.45) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL82995 0.77 CA1 (0.46) ALDH1A1CA2MMP1MMP8MMP13
SCHEMBL453332 0.77 MMP1 (0.51) ALDH1A1CA2KMT2ACYP2C9CYP2D6
SCHEMBL619004 0.76 LMNA (0.41) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL15833291 0.75 CA2 (0.51) LMNAALDH1A1TSHRNT5ECA2
SCHEMBL20741353 0.74 LMNA (0.50) LMNATDP1ALDH1A1TSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199681-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS EVONETIX LTD (GB) 2024-06-20 — — US claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 — — WO claimed
WO-2024081372-A1 PROCESSES FOR THE PREPARATION OF THE AGENT-LINKER CONJUGATE CL2A-SN-38 AND THE IMMUNOCONJUGATES SACITUZUMAB GOVITECAN AND LABETUZUMAB GOVETICAN GILEAD SCIENCES, INC. (US) 2024-04-18 — — WO claimed
US-20230235328-A1 NOVEL MORPHOLINO OLIGONUCLEOTIDE DERIVATIVES Nexoligo Co., Ltd. (KR) 2023-07-27 — — US claimed
WO-2023039068-A1 COMPOSITIONS AND METHODS FOR SYNTHESIS OF PEPTIDE NUCLEIC ACID INTERMEDIATES NEUBASE THERAPEUTICS, INC. (US) 2023-03-16 — — WO claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 — — EP claimed
EP-3720854-B1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING SPA (IT) 2021-04-21 — — EP claimed
US-20210047361-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS SILICON VALLEY BANK 2021-02-18 — — US claimed
EP-3743433-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS Evonetix Ltd (GB) 2020-12-02 — — EP claimed
US-10822371-B2 Solid phase synthesis of NIR fluorescent probe BRACCO IMAGING S.P.A. (IT) 2020-11-03 — — US claimed
EP-3720854-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE Bracco Imaging SpA (IT) 2020-10-14 — — EP claimed
US-20200317722-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING S.P.A. (IT) 2020-10-08 — — US claimed
WO-2019145713-A9 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS EVONETIX LTD (GB) 2020-08-06 — — WO claimed
EP-3609866-A1 THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS Evonetix Ltd (GB) 2020-02-19 — — EP claimed
WO-2019145713-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS EVONETIX LTD (GB) 2019-08-01 — — WO claimed
WO-2019110639-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING SPA (IT) 2019-06-13 — — WO claimed
EP-3400217-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2018-11-14 — — EP claimed
WO-2018189546-A1 THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS EVONETIX LTD (GB) 2018-10-18 — — WO claimed
US-9834528-B2 Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof MERCK SERONO S.A. (CH) 2017-12-05 — — US claimed
WO-2017118641-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF MERCK SERONO S.A. (CH) 2017-07-13 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235328-A1 NOVEL MORPHOLINO OLIGONUCLEOTIDE DERIVATIVES RNGTT, MPO, RNMT LMNA 3274/4885TDP1 773/4885ALDH1A1 2537/4885
US-20200317722-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE MKI67, SSTR5, AURKA LMNA 3265/4885TDP1 3853/4885ALDH1A1 3804/4885
US-20240199681-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS POLN, POLI, ADAR LMNA 319/4885TDP1 170/4885ALDH1A1 4015/4885
US-10822371-B2 Solid phase synthesis of NIR fluorescent probe MKI67, SSTR5, AURKA LMNA 3265/4885TDP1 3853/4885ALDH1A1 3804/4885
US-20210047361-A1 OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS POLN, POLI, ADAR LMNA 319/4885TDP1 170/4885ALDH1A1 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.