Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209447 | 0.91 | ALDH1A1 (0.41) | CTSBCTSSCTSKLMNATP53 | |
| SCHEMBL6210847 | 0.89 | KEAP1 (0.38) | SMN1; SMN2GAAKCNA5 | |
| SCHEMBL6211554 | 0.87 | KCNA5 (0.39) | CTSBCTSSCTSKLMNATP53 | |
| SCHEMBL6213867 | 0.86 | CHRM4 (0.40) | FKBP1ALMNASMYD3 | |
| SCHEMBL6254282 | 0.85 | CTSK (0.38) | CTSSCTSKGAAKCNA5 | |
| SCHEMBL6209450 | 0.85 | CXCR3 (0.43) | LMNATP53SMYD3GAA | |
| SCHEMBL6208718 | 0.84 | LMNA (0.42) | CTSKLMNASMN1; SMN2SMYD3GAA | |
| SCHEMBL6211570 | 0.83 | SLC6A5 (0.38) | LMNASMYD3 | |
| SCHEMBL6211038 | 0.83 | CTSK (0.41) | CTSKLMNASMYD3GAA | |
| SCHEMBL6212257 | 0.83 | POLB (0.40) | LMNASMN1; SMN2SMYD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |