SCHEMBL621646

SCHEMBL621646

Cc1nc2cccc(OCC(C)(C)C(=O)NC(C)C)c2c(N)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DGAT1 O75907 1/20 0.35
PIK3CD O00329 1/20 0.35
SSTR4 P31391 5/20 0.35
AAK1 Q2M2I8 3/20 0.33
DCPS Q96C86 2/20 0.33
SSTR1 P30872 1/20 0.32
KCNH2 Q12809 2/20 0.32
NCF1 P14598 1/20 0.32
PDE10A Q9Y233 1/20 0.32
SMYD3 Q9H7B4 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32
GAK O14976 1/20 0.32
HTR2B P41595 1/20 0.32
DAPK1 P53355 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29976534 1.00 MEN1 (0.38) MEN1KMT2ATP53HSD17B10DGAT1
SCHEMBL28451324 0.99 MEN1 (0.38) MEN1KMT2ATP53HSD17B10DGAT1
Phosphoric Acid SCHEMBL16606192 0.96 MEN1 (0.36) MEN1KMT2ATP53HSD17B10DGAT1
Sulfuric Acid SCHEMBL26630523 0.96 MEN1 (0.36) MEN1KMT2ATP53HSD17B10DGAT1
Sulfuric Acid SCHEMBL26630521 0.96 MEN1 (0.36) MEN1KMT2ATP53HSD17B10DGAT1
SCHEMBL620085 0.90 MEN1 (0.37) MEN1KMT2ATP53HSD17B10PIK3CD
SCHEMBL18824050 0.90 SSTR4 (0.36) MEN1KMT2ATP53HSD17B10DGAT1
SCHEMBL620482 0.90 SSTR4 (0.36) TP53HSD17B10DGAT1PIK3CDSSTR4
SCHEMBL619322 0.90 GABRP (0.41) MEN1KMT2ATP53HSD17B10
SCHEMBL10257493 0.89 KMT2A (0.40) MEN1KMT2ATP53HSD17B10PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025202907-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-02 WO claimed
EP-4623708-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-01 EP claimed
US-11186560-B2 Arthropod repellent chemicals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-11-30 US claimed
US-20190194158-A1 ARTHROPOD REPELLENT CHEMICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-06-27 US claimed
EP-3270692-A1 ANTHROPOD REPELLENT CHEMICALS The Regents of the University of California (US) 2018-01-24 EP claimed
US-20170369468-A1 ANTHROPOD REPELLENT CHEMICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-12-28 US claimed
WO-2016149567-A1 ANTHROPOD REPELLENT CHEMICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-09-22 WO claimed
US-20160272612-A1 ANTHROPOD REPELLENT CHEMICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-09-22 US claimed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 US disclosed
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
WO-2025202907-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-02 WO disclosed
EP-4623708-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-01 EP disclosed
US-20130041046-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. (US) 2013-02-14 US disclosed
US-20130041046-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. (US) 2013-02-14 US disclosed
US-20120041078-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 US disclosed
WO-2012021837-A2 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 WO disclosed
WO-2012021837-A2 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 WO disclosed
US-20120041078-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 MEN1 1930/4885KMT2A 2459/4885TP53 4879/4885
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 MEN1 1752/4885KMT2A 2702/4885TP53 1422/4885
US-20120041078-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER TFEB, TREH, SLC2A8 MEN1 2269/4885KMT2A 740/4885TP53 2058/4885
US-20190194158-A1 ARTHROPOD REPELLENT CHEMICALS DDT, TRPA1, DHODH MEN1 3217/4885KMT2A 4322/4885TP53 4339/4885
US-20160272612-A1 ANTHROPOD REPELLENT CHEMICALS DDT, HPD, TRPA1 MEN1 4124/4885KMT2A 3735/4885TP53 4259/4885
US-20130041046-A1 SWEET FLAVOR MODIFIER TAS2R5, TAS2R10, TAS2R50 MEN1 1566/4885KMT2A 1894/4885TP53 1393/4885
US-11186560-B2 Arthropod repellent chemicals DDT, TRPA1, DHODH MEN1 3217/4885KMT2A 4322/4885TP53 4339/4885
US-20170369468-A1 ANTHROPOD REPELLENT CHEMICALS DDT, HPD, TRPA1 MEN1 4124/4885KMT2A 3735/4885TP53 4259/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 MEN1 2841/4885KMT2A 733/4885TP53 1041/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 MEN1 3787/4885KMT2A 3953/4885TP53 2142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.