SCHEMBL6276680

SCHEMBL6276680

C=C(C(=C)C(=O)NC(C(C)C)S(=O)(=O)OC)C(=O)[O-].C=C(C)C(=O)OCCOC(C)=O.[Na+]

nearest known ligand 0.33

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119105 0.80 THRB (0.35) THRBTSHR
SCHEMBL8356573 0.79 TSHR (0.35) THRBTSHR
SCHEMBL7025308 0.70 THRB (0.33) THRBTSHR
Methacrylic Acid SCHEMBL8942525 0.70 ALDH1A1 (0.33)
Methacrylic Acid SCHEMBL31408187 0.66 THRB (0.61) THRBTSHR
SCHEMBL303014 0.66 THRB (0.65) THRBTSHR
SCHEMBL8761553 0.65 ALDH1A1 (0.38) THRBTSHR
Dimethylamine SCHEMBL28490825 0.65 THRB (0.59) THRBTSHR
SCHEMBL8501987 0.64 THRB (0.63) THRBTSHR
SCHEMBL28745043 0.64 THRB (0.63) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1102119-B1 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO LTD (JP) 2005-01-26 EP disclosed
US-6416924-B1 LIGHT SENSITIVE LAYER WITH EMULSIONS OF DIFFERENT SPEEDS AND INSENSITIVE LAYER COMPRISED OF HYDRAZINE, AMINE, ONIUM, DISULFIDE, AND HYDROXYMETHYL DERIVATIVES; LITTLE EXPOSURE UNEVENNESS CAUSED BY IMAGE SETTER FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US disclosed
EP-1102119-A2 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2001-05-23 EP disclosed
EP-0802451-B1 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO LTD (JP) 2000-07-26 EP disclosed
EP-0802451-A1 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 1997-10-22 EP disclosed