Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16278866 | 0.88 | ESR1 (0.69) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL9840621 | 0.88 | ESR1 (0.69) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL17797863 | 0.88 | ESR1 (0.69) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL23001352 | 0.87 | LMNA (0.54) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL43781 | 0.87 | ALDH1A1 (0.58) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL11569263 | 0.87 | ALDH1A1 (0.58) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL29988943 | 0.87 | ALDH1A1 (0.58) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL7601276 | 0.87 | ALDH1A1 (0.63) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL22832633 | 0.86 | ESR1 (0.72) | LMNACYP1A2TSHRESR1CYP2C19 | |
| SCHEMBL5709852 | 0.85 | ALDH1A1 (0.66) | LMNACYP1A2TSHRESR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110038-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | MITSUI CHEMICALS, INC. (JP) | 2021-09-07 | — | — | US | disclosed |
| US-20200030194-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2020-01-30 | — | — | US | disclosed |
| US-10470980-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | MITSUI CHEMICALS, INC. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| EP-3278787-A1 | POLYMERIZABLE MONOMER FOR DENTAL MATERIALS, COMPOSITION, ADHESIVE DENTAL MATERIAL, AND KIT | Mitsui Chemicals, Inc. (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-1627867-B1 | (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2058318-B1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-8129443-B2 | Inorganic oxide nanoparticles having an X-ray contrast property and high transparency, a functionalized silanediol monomeric or oligomeric surface modifier, and a polymerizable compound; dental composites | SUN MEDICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7534909-B2 | (Meth) acrylic ester compound and use thereof | MITSUI CHEMICALS, INC. (JP) | 2009-05-19 | — | — | US | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20080182919-A1 | Dental Restorative Composition | SUN MEDICAL CO., LTD. (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1854447-A1 | DENTAL RESTORATION MATERIAL COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20070078198-A1 | (Meth) acrylic ester compound and use thereof | MITSUI CHEMICALS, INC. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1627867-A1 | (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2006-02-22 | — | — | EP | disclosed |
| US-20050123762-A1 | Polymerizable composition, cured object obtained therefrom, and composite material | SUN MEDICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| US-20040039080-A1 | Dental material and composition | SUN MEDICAL CO., LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-1334711-A1 | DENTAL MATERIAL AND COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| EP-0588534-B1 | Radiation curing ink | HAYAKAWA RUBBER (JP) | 1998-12-02 | — | — | EP | disclosed |
| EP-0003872-A1 | Substituted benzoic acid esters, compositions containing them, combinations thereof with photoinitiators and methods of making cured plastics compositions using them | WARD BLENKINSOP AND COMPANY LIMITED (GB) | 1979-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039080-A1 | Dental material and composition | RPS12, RPS21, RPS14 | LMNA 3299/4885CYP1A2 3686/4885TSHR 3057/4885 |
| US-20200030194-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | ACTN1, SMCHD1, CAPZA1 | LMNA 1974/4885CYP1A2 4859/4885TSHR 4160/4885 |
| US-20080182919-A1 | Dental Restorative Composition | PARG, PARN, FHIT | LMNA 682/4885CYP1A2 4433/4885TSHR 3228/4885 |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | CAD, PPIP5K2, SLC20A1 | LMNA 1188/4885CYP1A2 4871/4885TSHR 4810/4885 |
| US-10470980-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | HRH3, HRH1, HRH2 | LMNA 2937/4885CYP1A2 2042/4885TSHR 861/4885 |
| US-11110038-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | ACTN1, SMCHD1, CAPZA1 | LMNA 1974/4885CYP1A2 4859/4885TSHR 4160/4885 |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | HRH3, HRH1, HRH2 | LMNA 2937/4885CYP1A2 2042/4885TSHR 861/4885 |
| US-20070078198-A1 | (Meth) acrylic ester compound and use thereof | METTL14, PAM, TAS2R41 | LMNA 4549/4885CYP1A2 897/4885TSHR 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.