SCHEMBL637784

SCHEMBL637784

O=C([O-])CC(S)C(=O)[O-].[Na+].[Na+]

nearest known ligand 0.52

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 known ✓ P22748 4/20 0.52
CA2 known ✓ P00918 1/20 0.48
CA1 known ✓ P00915 1/20 0.33
CTSL P07711 1/20 0.44
CASP1 P29466 1/20 0.36
SLC22A16 Q86VW1 1/20 0.36
CPT2 P23786 1/20 0.33
CPT1A P50416 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27742460 0.97 CA4 (0.50) CA4CA2CTSLCASP1SLC22A16
Potassium Ion SCHEMBL31206140 0.95 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
SCHEMBL1546186 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
SCHEMBL29199237 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
SCHEMBL7899819 0.94 CTSL (0.50) CA4CA2CTSLCASP1SLC22A16
Silver SCHEMBL6741767 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
Potassium Ion SCHEMBL637500 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
SCHEMBL6741776 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
Lithium Ion SCHEMBL29028816 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16
Zinc Ion SCHEMBL6051610 0.94 CA4 (0.48) CA4CA2CTSLCASP1SLC22A16

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113322225-A Additive for human embryonic stem cell in vitro amplification and amplification method 郑州优倍得生物科技有限公司 2021-08-31 CN claimed
JP-55073350-A None JP disclosed
US-20260070068-A1 AMMONIATED POLYCARBAMIDE SEPARATION AIDS FOR MINERAL FLOTATION HEXION INC. (US) 2026-03-12 US disclosed
US-11578327-B2 Oligonucleotide therapy for Wilson disease DEEP GENOMICS INCORPORATED (CA) 2023-02-14 US disclosed
CN-113322225-A Additive for human embryonic stem cell in vitro amplification and amplification method 郑州优倍得生物科技有限公司 2021-08-31 CN disclosed
CN-113322225-A Additive for human embryonic stem cell in vitro amplification and amplification method 郑州优倍得生物科技有限公司 2021-08-31 CN disclosed
US-20210032629-A1 OLIGONUCLEOTIDE THERAPY FOR WILSON DISEASE DEEP GENOMICS INCORPORATED (CA) 2021-02-04 US disclosed
EP-3752614-A1 OLIGONUCLEOTIDE THERAPY FOR WILSON DISEASE Deep Genomics Incorporated (CA) 2020-12-23 EP disclosed
CN-112041439-A Oligonucleotide therapy for wilson's disease 深度基因组学公司 2020-12-04 CN disclosed
WO-2020045454-A1 RUBBER COMPOSITION, METAL-RUBBER COMPOSITE MOLDED BODY AND METHOD FOR PRODUCING METAL-RUBBER COMPOSITE MOLDED BODY 住友化学株式会社 2020-03-05 WO disclosed
US-20090110889-A1 CONDUCTIVE PATTERN FORMATION INK, CONDUCTIVE PATTERN AND WIRING SUBSTRATE SEIKO EPSON CORPORATION (JP) 2009-04-30 US disclosed
US-20090090272-A1 CONDUCTIVE PATTERN FORMATION INK, CONDUCTIVE PATTERN AND WIRING SUBSTRATE SEIKO EPSON CORPORATION (JP) 2009-04-09 US disclosed
US-20090087580-A1 INK COMPOSITION, PATTERN FORMATION METHOD AND DROPLET DISCHARGE DEVICE SEIKO EPSON CORPORATION (JP) 2009-04-02 US disclosed
US-7367999-B2 Ultrafine particles and method and apparatus for producing the same FUJIFILM CORPORATION (JP) 2008-05-06 US disclosed
US-20050126340-A1 Ultrafine particles and method and apparatus for producing the same FUJI PHOTO FILM CO., LTD. 2005-06-16 US disclosed
US-20030019327-A1 Ultrafine particles and method and apparatus for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2003-01-30 US disclosed
US-4622131-A DEPRESSANT BLEND PHILLIPS PETROLEUM COMPANY (US) 1986-11-11 US disclosed
US-4533466-A FOR MINERAL RECOVERY USING FROTH FLOTATION PHILLIPS PETROLEUM COMPANY (US) 1985-08-06 US disclosed
US-4482480-A ORE FLOATION AGENTS, TRITHIONCARBONATE DERIVATIVES PHILLIPS PETROLEUM COMPANY (US) 1984-11-13 US disclosed
JP-S5573350-A DETERGENT FOR ION EXCHANGE RESIN NITTO KAKO KK 1980-06-03 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070068-A1 AMMONIATED POLYCARBAMIDE SEPARATION AIDS FOR MINERAL FLOTATION FOS, SETD1A, SETDB1 CA4 1570/4885CA2 1352/4885CA1 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.