Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL15572660 | 0.96 | CA2 (0.52) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL11436838 | 0.95 | CA2 (0.56) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL31187513 | 0.95 | CA2 (0.62) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL725833 | 0.95 | CA2 (0.62) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15571521 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15571213 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL9930191 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15573521 | 0.91 | CA2 (0.58) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL105996 | 0.91 | CA2 (0.59) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15570534 | 0.90 | CA2 (0.47) | CA2CA4CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364322-B2 | Naphthalene-containing polymers and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180208716-A1 | NAPHTHALENE-CONTAINING POLYMERS AND METHODS OF MAKING THE SAME | Alliance for Energy Innovation, LLC | 2018-07-26 | — | — | US | disclosed |
| US-20150238948-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-08-27 | — | — | US | disclosed |
| EP-2888043-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-01 | — | — | EP | disclosed |
| EP-2475000-B1 | PROCESSING AGENT COMPOSITION FOR SEMICONDUCTOR SURFACE AND METHOD FOR PROCESSING SEMICONDUCTOR SURFACE USING SAME | WAKO PURE CHEM IND LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-9034810-B2 | Processing agent composition for semiconductor surface and method for processing semiconductor surface using same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| WO-2014032004-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2014-02-27 | — | — | WO | disclosed |
| EP-2475000-A1 | PROCESSING AGENT COMPOSITION FOR SEMICONDUCTOR SURFACE AND METHOD FOR PROCESSING SEMICONDUCTOR SURFACE USING SAME | Wako Pure Chemical Industries, Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |
| US-20120157368-A1 | PROCESSING AGENT COMPOSITION FOR SEMICONDUCTOR SURFACE AND METHOD FOR PROCESSING SEMICONDUCTOR SURFACE USING SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-21 | — | — | US | disclosed |
| EP-1400524-B1 | Tetrakis(fluoroaryl) borate/ether complexes and process for preparing the same | NIPPON CATALYTIC CHEM IND (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6380435-B2 | CHEMICAL INTERMEDIATE FOR POLYMERIZATION CATALYST | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-04-30 | — | — | US | disclosed |
| US-6281389-B1 | MIXING WITH SOLVENT; DISTILLATION | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| US-20010014739-A1 | Purifying process of tetrakis (fluoroaryl) borate.magnesium halide, tetrakis (fluoroaryl) borate.ether complex and producing process of the same, and producing process of tetrakis (fluoroaryl) borate derivative | NIPPON SHOKUBAI CO., LTD. | 2001-08-16 | — | — | US | disclosed |
| US-6215025-B1 | Method for purifying tetrakis (fluoroaryl) borate/magnesium halide, tetrakis (fluoroaryl) borate/ether complex and process for preparing the same, and process for preparing tetrakis (fluoroaryl) borate derivative | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0985672-A2 | Method for purifying tetrakis(fluoroaryl)borate compounds | Nippon Shokubai Co., Ltd. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0913400-A1 | METHOD FOR PURIFYING TETRAKIS(FLUOROARYL) BORATE/MAGNESIUM HALIDE, TETRAKIS(FLUOROARYL) BORATE/ETHER COMPLEX AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING TETRAKIS(FLUOROARYL) BORATE DERIVATIVE | Nippon Shokubai Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| EP-0194058-B1 | PROCESS OF PREPARING POLYAMIDES AND/OR POLYIMIDES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-4795795-A | Catalytic preparation of polyamide or polyamide-polymide with N,N'-dimethyl alkylene urea solvent | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0194058-A2 | Process of preparing polyamides and/or polyimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4395531-A | Process for the preparation of polyamide compounds by the reaction of polycarboxylic acids with diisocyanates in the presence of at least one mono-alkali metal salt of dicarboxylic acid | MITSUI TOATSU CHEMICAL INCORPORATED (JP) | 1983-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014739-A1 | Purifying process of tetrakis (fluoroaryl) borate.magnesium halide, tetrakis (fluoroaryl) borate.ether complex and producing process of the same, and producing process of tetrakis (fluoroaryl) borate derivative | BMX, BRIX1, CYP4X1 | CA2 590/4885CA4 283/4885CA1 939/4885 |
| US-20180208716-A1 | NAPHTHALENE-CONTAINING POLYMERS AND METHODS OF MAKING THE SAME | NCL, NUCB2, NOC2L | CA2 4307/4885CA4 3751/4885CA1 2750/4885 |
| US-20150238948-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | LCT, AGL, MGAM | CA2 1626/4885CA4 583/4885CA1 1072/4885 |
| US-10364322-B2 | Naphthalene-containing polymers and methods of making the same | NCL, NUCB2, NOC2L | CA2 4307/4885CA4 3751/4885CA1 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.