Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.62 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.62 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.56 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL31187513 | 1.00 | CA2 (0.62) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15573521 | 0.96 | CA2 (0.58) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL11436838 | 0.95 | CA2 (0.56) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL6378446 | 0.95 | CA2 (0.56) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL9930191 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15571521 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15571213 | 0.93 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL1396770 | 0.92 | CA2 (0.54) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL15572660 | 0.91 | CA2 (0.52) | CA2CA4CA1CA9CA12 | |
| Isophthalic Acid SCHEMBL6280491 | 0.91 | CA2 (0.60) | CA2CA4CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630710-B1 | 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2026-05-19 | — | — | US | claimed |
| CN-117181077-A | Smokeless sulfur-free firework whistle agent mixing device and method | 万载县建坤化工有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-110981653-B | Smokeless and sulfur-free firework flute sound agent and preparation method thereof | 北京理工大学 | 2020-12-01 | — | — | CN | claimed |
| CN-110981653-A | Smokeless and sulfur-free firework flute sound agent and preparation method thereof | 北京理工大学 | 2020-04-10 | — | — | CN | claimed |
| US-8716404-B1 | Polyesters modified by a combination of ionomer and fatty acid salts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-06 | — | — | US | claimed |
| US-8609770-B2 | Polyesters modified by a combination of ionomer and organic acid salts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-17 | — | — | US | claimed |
| EP-2235108-B1 | POLYESTERS MODIFIED BY A COMBINATION OF IONOMER AND ORGANIC ACID SALTS | DU PONT (US) | 2013-02-27 | — | — | EP | claimed |
| EP-2235107-B1 | TOUGHENED POLY(TRIMETHYLENE TEREPHTHALATE) COMPOSITION WITH REDUCED MELT VISCOSITY | DU PONT (US) | 2012-09-26 | — | — | EP | claimed |
| US-8242209-B2 | Renewable polyester and carboxylic acid salt as nucleator; moldings; improved stiffness and impact strength | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-14 | — | — | US | claimed |
| JP-4694094-B2 | — | — | 2011-06-01 | — | — | JP | claimed |
| US-20090192268-A1 | POLYESTERS MODIFIED BY A COMBINATION OF IONOMER AND ORGANIC ACID SALTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | US | claimed |
| US-20090192266-A1 | TOUGHENED POLY(TRIMETHYLENE TEREPHTHALATE) COMPOSITION WITH REDUCED MELT VISCOSITY | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | US | claimed |
| WO-2009094362-A1 | TOUGHENED POLY(TRIMETHYLENE TEREPHTHALATE) COMPOSITION WITH REDUCED MELT VISCOSITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | claimed |
| EP-1339781-B1 | METHOD TO PRODUCE A POLY(TRIMETHYLENE TEREPHTHALATE) FILM | DU PONT (US) | 2008-12-31 | — | — | EP | claimed |
| US-6818160-B2 | Nucleating polypropylene terephthalate prior to film formation by adding monosodium salt of aromatic dicarboxylic acid during resin synthesis, and controlling quench temperature during casting of film; reduce brittleness of the film on thermal aging | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-16 | — | — | US | claimed |
| JP-2004522814-A | — | — | 2004-07-29 | — | — | JP | claimed |
| EP-1339781-A1 | METHOD TO PRODUCE A POLY(TRIMETHYLENE TEREPHTHALATE) FILM | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2003-09-03 | — | — | EP | claimed |
| EP-1114095-B1 | NUCLEATING AGENT FOR POLYESTERS | DU PONT (US) | 2003-06-04 | — | — | EP | claimed |
| US-20020117081-A1 | Method to improve properties of poly (Trimethylene terephthalate) film | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-08-29 | — | — | US | claimed |
| WO-2002040583-A1 | METHOD TO PRODUCE A POLY(TRIMETHYLENE TEREPHTHALATE) FILM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-05-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630710-B1 | 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture | GRIN2D, SMCHD1, GRIN2C | CA2 55/4885CA4 416/4885CA1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.