Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875254 | 0.79 | RXRA (0.45) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL11562036 | 0.68 | TRIM24 (0.43) | FABP4FABP5MAPK1HDAC3ADRA1A | |
| SCHEMBL411981 | 0.63 | APEX1 (0.54) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL4314440 | 0.61 | FABP4 (1.00) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL30573159 | 0.61 | FABP4 (1.00) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL29954757 | 0.60 | TRIM24 (0.46) | FABP4FABP5SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5170220 | 0.60 | FABP4 (0.56) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL7344985 | 0.59 | KDM4E (0.49) | FABP4FABP5HSD17B10KDM4EMAPK1 | |
| SCHEMBL29129893 | 0.59 | SMN1; SMN2 (0.69) | HSD17B10MAPK1HDAC3ADRA1AHDAC4 | |
| SCHEMBL25465028 | 0.58 | PTGS1 (0.53) | FABP4FABP5MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4193862-A | — | — | None | — | — | JP | disclosed |
| CN-118806826-A | A tea for resolving hard mass and its preparation method | 佛山市人铁智谷大药房有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-117865945-A | 2-aldehyde pyrrole butyric acid derivative, preparation method and application thereof | 天津现代创新中药科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20200385347-A1 | PYRROLE COMPOUND | MYCOLOGY TECHNO.CORP. (JP) | 2020-12-10 | — | — | US | disclosed |
| US-20200385347-A1 | PYRROLE COMPOUND | MYCOLOGY TECHNO.CORP. (JP) | 2020-12-10 | — | — | US | disclosed |
| CN-103073479-B | Method for preparing natural pyrrole derivative from plant brassica rapa L. by extraction, purification and separation | UNIV SICHUAN | 2015-02-04 | — | — | CN | disclosed |
| CN-103073479-A | Method for preparing natural pyrrole derivative from plant brassica rapa L. by extraction, purification and separation | UNIV SICHUAN | 2013-05-01 | — | — | CN | disclosed |
| US-20050163801-A1 | Method of inducing apoptosis and compositions therefor | KYOWA ENGINEERING CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1454626-A1 | METHOD OF INDUCING APOPTOSIS AND COMPOSITIONS THEREFOR | Sundory Co., Ltd. (JP) | 2004-09-08 | — | — | EP | disclosed |
| JP-H04193862-A | 4-(2-FORMYL-5-HYDROXYMETHYL-PYRROL-1-YL)BUTYRIC ACID AND TASTE AND FLAVOR-IMPROVING AGENT FOR TABACCO COMPOSED THEREOF | JAPAN TOBACCO INC | 1992-07-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050163801-A1 | Method of inducing apoptosis and compositions therefor | TREH, ACIN1, WAPL | FABP4 692/4885FABP5 2611/4885HSD17B10 2522/4885 |
| US-20200385347-A1 | PYRROLE COMPOUND | PYCR1, ALDH18A1, FKBP1B | FABP4 2657/4885FABP5 2289/4885HSD17B10 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.