Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 2/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495924 | 1.00 | CPA3 (0.65) | CPA3KEAP1TRPA1NAALAD2FFAR1 | |
| SCHEMBL6495926 | 1.00 | CPA3 (0.65) | CPA3KEAP1TRPA1NAALAD2FFAR1 | |
| SCHEMBL3447583 | 0.89 | CPA3 (0.56) | CPA3KEAP1TRPA1NAALAD2FFAR1 | |
| SCHEMBL28179822 | 0.85 | TRPA1 (0.53) | CPA3KEAP1TRPA1SLC15A1CYP1A2 | |
| SCHEMBL6907271 | 0.85 | ALDH1A1 (0.55) | CPA3KEAP1TRPA1SLC15A1CYP1A2 | |
| SCHEMBL14698289 | 0.83 | HDAC3 (0.53) | CPA3KEAP1TRPA1CYP1A2TRPV1 | |
| SCHEMBL16452830 | 0.83 | FFAR1 (0.51) | CPA3NAALAD2FFAR1CYP1A2SMN1; SMN2 | |
| SCHEMBL16452836 | 0.83 | CPA3 (0.46) | CPA3TRPA1NAALAD2FFAR1 | |
| SCHEMBL9557217 | 0.83 | CPA3 (0.46) | CPA3KEAP1TRPA1NAALAD2FFAR1 | |
| SCHEMBL5105980 | 0.83 | TRPA1 (0.52) | CPA3TRPA1CYP1A2TRPV1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2005-05-26 | — | — | US | claimed |
| US-20030096019-A1 | Methods of using norfluoxetine | SEPRACOR INC. | 2003-05-22 | — | — | US | claimed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2005-05-26 | — | — | US | disclosed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096019-A1 | Methods of using norfluoxetine | NGF, TPH2, ALOX5 | CPA3 890/4885KEAP1 469/4885TRPA1 786/4885 |
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | GABRB1, GABRA1, GABRA5 | CPA3 1449/4885KEAP1 3574/4885TRPA1 938/4885 |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | KRT18, DSP, DPYD | CPA3 3606/4885KEAP1 1505/4885TRPA1 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.