Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 13/20 | 0.58 |
| ▸ | CA1 known ✓ | P00915 | 12/20 | 0.58 |
| ▸ | CA12 known ✓ | O43570 | 12/20 | 0.58 |
| ▸ | CA9 | Q16790 | 12/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879352 | 0.97 | CA2 (0.60) | CA2CA1CA12CA9HTT | |
| SCHEMBL16290412 | 0.92 | CA2 (0.60) | CA2CA1CA12CA9HTT | |
| SCHEMBL27470250 | 0.92 | CA2 (0.60) | CA2CA1CA12CA9HTT | |
| Potassium Ion SCHEMBL7562133 | 0.92 | CA2 (0.64) | CA2CA1CA12CA9HTT | |
| Potassium Ion SCHEMBL11805822 | 0.92 | CA2 (0.64) | CA2CA1CA12CA9HTT | |
| Ammonia Solution, Strong SCHEMBL25306979 | 0.90 | CA2 (0.58) | CA2CA1CA12CA9HTT | |
| SCHEMBL4437819 | 0.89 | CA2 (0.52) | CA2CA1CA12CA9HTT | |
| SCHEMBL4443515 | 0.86 | CA2 (0.54) | CA2CA1CA12CA9HTT | |
| SCHEMBL9753805 | 0.76 | CA12 (0.91) | CA2CA1CA12CA9HTT | |
| SCHEMBL3772058 | 0.76 | CA12 (0.95) | CA2CA1CA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506132-B1 | Method for removal of mercury in exhaust gas | ORIENTAL TECHNICAL RESEARCH IN (JP) | 1996-02-14 | — | — | EP | claimed |
| JP-5208117-A | — | — | None | — | — | JP | disclosed |
| CN-110683975-B | Synthesis method of dialkyl amino alkyl dithioformate | 成都理工大学 | 2021-04-09 | — | — | CN | disclosed |
| CN-110683975-A | Synthesis method of dialkyl amino alkyl dithioformate | 成都理工大学 | 2020-01-14 | — | — | CN | disclosed |
| EP-2240258-B1 | THE COMPLEXATION AND REMOVAL OF HEAVY METALS FROM FLUE GAS DESULFURIZATION SYSTEMS | NALCO CO (US) | 2015-08-12 | — | — | EP | disclosed |
| US-20050008568-A1 | Technetium or rhenium complexes, radiopharmaceutical products comprising them | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | disclosed |
| EP-1453841-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003044031-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
| EP-0506132-B1 | Method for removal of mercury in exhaust gas | ORIENTAL TECHNICAL RESEARCH IN (JP) | 1996-02-14 | — | — | EP | disclosed |
| JP-H05208117-A | REMOVAL OF MERCURY IN EXHAUST GAS | ORIENTAL GIKEN KOGYO KK | 1993-08-20 | — | — | JP | disclosed |
| EP-0506132-A1 | Method for removal of mercury in exhaust gas | Oriental Technical Research Industry Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |
| US-4683316-A | Method of preparation of dithiocarbamate complexes of molybdenum (VI) | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008568-A1 | Technetium or rhenium complexes, radiopharmaceutical products comprising them | TSHR, MRPS35, TFRC | CA2 1554/4885CA1 2501/4885CA12 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.