Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 7/20 | 0.95 |
| ▸ | CA1 known ✓ | P00915 | 7/20 | 0.95 |
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.95 |
| ▸ | CA9 | Q16790 | 7/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL14843848 | 0.95 | CA12 (1.00) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL5826309 | 0.95 | CA12 (0.95) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL6060070 | 0.95 | CA12 (0.95) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL3879352 | 0.78 | CA2 (0.60) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL11174169 | 0.78 | CA12 (0.67) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL3077426 | 0.76 | CA12 (0.64) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL6515026 | 0.76 | CA2 (0.58) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL1267862 | 0.74 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL3071219 | 0.74 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL10742927 | 0.74 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117861863-A | Inhibitor of non-molybdenum sulfide ore and application of inhibitor in metal sulfide ore flotation separation | 江西理工大学 | 2024-04-12 | — | — | CN | disclosed |
| EP-1554241-B1 | S-(ALPHA,ALPHA'-DISUBSTITUTED-ALPHA\"-ACETIC ACID) SUBSTITUTED DITHIOCARBONATE DERIVATIVES FOR CONTROLLED RADICAL POLYMERISATIONS, PROCESS AND POLYMERS MADE THEREFROM | LUBRIZOL ADVANCED MAT INC (US) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013050426-A1 | CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE | UNIVERSITETET I OSLO (NO) | 2013-04-11 | — | — | WO | disclosed |
| US-7851582-B2 | S-(α, α′-disubstituted-α″-acetic acid)—substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7498456-B2 | S-(α, α′-disubstituted-α″-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerization, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080214773-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) - Substituted Dithiocarbonate Derivatives For Controlled Radical Polymerizations, Process and Polymers Made Therefrom | LAI JOHN TA-YUAN | 2008-09-04 | — | — | US | disclosed |
| US-7335788-B2 | S-(α, α′-disubstituted-α″-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-20070167571-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) Substituted Dithiocarbonate Derivatives for Controlled Radical Polymerizations, Process and Polymers Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2007-07-19 | — | — | US | disclosed |
| US-7205368-B2 | S-(α, α′-disubstituted-α′ ′-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | NOVEON, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| WO-2005080326-A1 | TOUGHENED VINYL ESTER RESINS | NOVEON IP HOLDINGS CORP. (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1453841-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2004037780-A1 | S-(a, a’ -DISUBSTITUTED-a” -ACETIC ACID) SUBSTITUTED DITHIOCARBONATE DERIVATIVES FOR CONTROLLED RADICAL POLYMERIZATIONS, PROCESS AND POLYMERS MADE THEREFROM | NOVEON IP HOLDINGS CORP. (US) | 2004-05-06 | — | — | WO | disclosed |
| US-20040073056-A1 | S-(alpha, alpha'-disubstituted-alpha\"-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2004-04-15 | — | — | US | disclosed |
| EP-1089723-A4 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2003-07-16 | — | — | EP | disclosed |
| US-20030120101-A1 | S-(alpha, alpha'-disubstituted-alpha' '-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2003-06-26 | — | — | US | disclosed |
| WO-2003044031-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
| CN-1315856-A | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor | MEDINOX INC (US) | 2001-10-03 | — | — | CN | disclosed |
| EP-1089723-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | Medinox, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999066918-A9 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999066918-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120101-A1 | S-(alpha, alpha'-disubstituted-alpha' '-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | TST, SRM, ACMSD | CA12 1776/4885CA1 1482/4885CA2 1854/4885 |
| US-20080214773-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) - Substituted Dithiocarbonate Derivatives For Controlled Radical Polymerizations, Process and Polymers Made Therefrom | TST, ACMSD, ETFA | CA12 1922/4885CA1 1544/4885CA2 1798/4885 |
| US-20070167571-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) Substituted Dithiocarbonate Derivatives for Controlled Radical Polymerizations, Process and Polymers Made Therefrom | TST, ACMSD, SRM | CA12 1670/4885CA1 1345/4885CA2 1681/4885 |
| US-20040073056-A1 | S-(alpha, alpha'-disubstituted-alpha\"-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | TST, ACMSD, SRM | CA12 1670/4885CA1 1345/4885CA2 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.