Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL7709463 | 0.92 | CA1 (0.48) | FABP3EPHX2 | |
| Oleic Acid SCHEMBL6519043 | 0.90 | FABP3 (0.63) | FABP3EPHX2LPAR1 | |
| Oleic Acid SCHEMBL20162207 | 0.86 | TERT (0.64) | EPHX2 | |
| Oleamide SCHEMBL9810589 | 0.86 | FAAH (0.64) | EPHX2LPAR1 | |
| Oleic Acid SCHEMBL28571631 | 0.86 | FABP3 (0.80) | FABP3 | |
| Oleamide SCHEMBL27903270 | 0.85 | FAAH (0.62) | EPHX2LPAR1 | |
| SCHEMBL27672168 | 0.85 | EPHX2 (0.57) | EPHX2LPAR1 | |
| Oleic Acid SCHEMBL28287037 | 0.85 | FABP3 (0.69) | FABP3EPHX2 | |
| Oleic Acid SCHEMBL7686924 | 0.84 | FABP3 (0.83) | FABP3 | |
| Oleic Acid SCHEMBL11491299 | 0.84 | FABP3 (0.83) | FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9144554-B2 | Topical compositions for use in the prevention and/or treatment of dermatitis | CUTRUPI CARMELO (IT) | 2015-09-29 | — | — | US | claimed |
| CN-112715559-A | Agricultural insecticidal composition containing sulfenamide and lambda-cyhalothrin and application thereof | 杭州宇龙化工有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112655713-A | Agricultural insecticidal composition containing sulfenamide and flonicamid and application thereof | 杭州宇龙化工有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-109566628-B | Acaricidal composition and application thereof | 沈阳中化农药化工研发有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-109479883-B | Insecticidal and acaricidal composition containing bactericide or bactericide (virus) killing agent | 沈阳中化农药化工研发有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-107743976-B | Insecticidal and acaricidal composition | 沈阳中化农药化工研发有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111096335-A | Soil fumigant and application thereof | 浙江泰达作物科技有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-107889824-B | Insecticidal and acaricidal composition | 沈阳中化农药化工研发有限公司 | 2020-02-14 | — | — | CN | disclosed |
| US-9144554-B2 | Topical compositions for use in the prevention and/or treatment of dermatitis | CUTRUPI CARMELO (IT) | 2015-09-29 | — | — | US | disclosed |
| US-8342640-B2 | Image forming method | FUJIFILM CORPORATION (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20110050788-A1 | IMAGE FORMING METHOD | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |