Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321705 | 1.00 | PPARA (0.54) | PPARAPPARGCTSKTACR1FOLH1 | |
| SCHEMBL22144256 | 0.91 | CTSK (0.53) | CTSKTACR1CTRB1CTSLCTSB | |
| SCHEMBL17860731 | 0.91 | CTSK (0.53) | CTSKTACR1CTRB1CTSLCTSB | |
| SCHEMBL15055671 | 0.89 | KYNU (0.60) | CTSKTACR1SIRT2SIRT1CTRB1 | |
| SCHEMBL15055673 | 0.89 | KYNU (0.60) | CTSKTACR1SIRT2SIRT1CTRB1 | |
| SCHEMBL18248139 | 0.88 | PPARA (0.56) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL17685903 | 0.88 | PPARA (0.56) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL8387978 | 0.88 | FOLH1 (0.65) | PPARAPPARGCTSKFOLH1SIRT2 | |
| SCHEMBL10421088 | 0.88 | FOLH1 (0.62) | PPARAPPARGCTSKTACR1FOLH1 | |
| SCHEMBL1701581 | 0.87 | CTSL (0.65) | PPARAPPARGCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110857286-B | Preparation method of micromolecule yNA with biological activity | 上海交通大学 | 2022-12-09 | — | — | CN | claimed |
| CN-110857286-A | Preparation method of micromolecule yNA with biological activity | 上海交通大学 | 2020-03-03 | — | — | CN | claimed |
| US-20230406885-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2023-12-21 | — | — | US | disclosed |
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | US | disclosed |
| EP-3898594-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113195455-A | Herbicidal cinnolinium compounds | 先正达农作物保护股份公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-1268469-B1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI SYNTHELABO (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-6680329-B2 | N-(heterocyclyl)benzene or pyridinesulphonamides as antithrombotic agents and anticoagulants | SANOFI-SYNTHELABO (FR) | 2004-01-20 | — | — | US | disclosed |
| US-20030207920-A1 | N-(heterocyclyl)benzene or pyridinesulphonamides as antithrombotic agents and anticoagulants | SANOFI-AVENTIS (FR) | 2003-11-06 | — | — | US | disclosed |
| EP-1268469-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070736-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406885-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | IL1A, IL1B, IL1R1 | PPARA 3131/4885PPARG 3427/4885CTSK 850/4885 |
| US-20030207920-A1 | N-(heterocyclyl)benzene or pyridinesulphonamides as antithrombotic agents and anticoagulants | PROC, VKORC1, SERPINC1 | PPARA 2671/4885PPARG 1758/4885CTSK 3537/4885 |
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | DDT, DERL1, CES2 | PPARA 1050/4885PPARG 772/4885CTSK 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.