Ether

Ether

SCHEMBL660656

CCOCC.CS(=O)(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
CA2 P00918 5/20 0.37
CA1 P00915 3/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32
TP53 P04637 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
USP2 O75604 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL5321749 0.91 ALDH1A1 (0.42) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL38466 0.90 CA5A (0.43) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL27570944 0.90 CA5A (0.43) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL14342973 0.87 ALDH1A1 (0.38) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL1095738 0.87 CA5A (0.40) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL19813170 0.87 CA5A (0.40) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL28102344 0.87 CA5A (0.40) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL9221305 0.87 CA5A (0.40) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL828632 0.87 CA5A (0.40) ALDH1A1CA2CA1MGAMGAA
Ether SCHEMBL6357672 0.87 ALDH1A1 (0.38) ALDH1A1CA2CA1MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024123771-A1 SYSTEMS AND METHODS FOR AIR SANITIZATION USING FORMULAS CONTAINING AN ORGANIC ACID THE CLOROX COMPANY (US) 2024-06-13 WO disclosed
US-20240182817-A1 STABLE HYPOHALITE CONCENTRATE AND DILUTION SYSTEM THE CLOROX COMPANY 2024-06-06 US disclosed
US-20240181111-A1 SYSTEMS AND METHODS FOR AIR SANITIZATION USING FORMULAS CONTAINING AN ORGANIC ACID THE CLOROX COMPANY 2024-06-06 US disclosed
US-11932833-B2 Stable activated peroxide sanitizing liquid compositions without added phosphorous compounds or cationic surfactants THE CLOROX COMPANY (US) 2024-03-19 US disclosed
WO-2024054747-A1 QUAT-BASED COMPOSTABLE AND BIODEGRADABLE PRE-MOISTENED CLEANING AND DISINFECTING WIPES SYSTEM WITH PARTICULAR SURFACE FRICTIONAL CHARACTERISTICS THE CLOROX COMPANY (US) 2024-03-14 WO disclosed
US-20240076582-A1 BURSTABLE SPORICIDAL CLEANING WIPE SYSTEM FOR C. DIFFICILE SPORES THE CLOROX COMPANY 2024-03-07 US disclosed
US-20240076581-A1 Quat-Based Compostable and Biodegradable Pre-Moistened Cleaning and Disinfecting Wipes System with Particular Surface Frictional Characteristics THE CLOROX COMPANY 2024-03-07 US disclosed
US-11845916-B2 Burstable sporicidal cleaning wipe system containing stabilized hypochlorite THE CLOROX COMPANY (US) 2023-12-19 US disclosed
US-20230354815-A1 BLEACH COMPOSITIONS THE CLOROX COMPANY 2023-11-09 US disclosed
US-20230301299-A1 DISINFECTING FORMULATIONS WITH CARVACROL THE CLOROX COMPANY 2023-09-28 US disclosed
US-20110052726-A1 SOLID-LAYERED BLEACH COMPOSITIONS AND METHODS OF USE THE CLOROX COMPANY (US) 2011-03-03 US disclosed
WO-2010148305-A1 METHODS AND COMPOSITIONS FOR PREPARATION OF AMPHETAMINE CONJUGATES AND SALTS THEREOF CAMBREX CHARLES CITY, INC. (US) 2010-12-23 WO disclosed
US-20090264431-A1 NOVEL CATHEPSIN C INHIBITORS AND THEIR USE GLAXO GROUP LIMITED (GB) 2009-10-22 US disclosed
WO-2009117278-A2 PROCESSES FOR PREPARING (AMINO-PYRAZOLOPYRIDINYL)METHOXY SUBSTITUTED BIARYL ETHERS MERCK & CO., INC. (US) 2009-09-24 WO disclosed
WO-2009026197-A1 NOVEL CATHEPSIN C INHIBITORS AND THEIR USE GLAXO GROUP LIMITED (GB) 2009-02-26 WO disclosed
CN-101128420-A Crystals of ladostigil tartrate, methods of production and pharmaceutical compositions thereof TEVA PHARMA (IL) 2008-02-20 CN disclosed
US-5713988-A LABELS FOR CARDBOARD BOXES, METAL OR PLASTIC CONTAINERS CABOT CORPORATION (US) 1998-02-03 US disclosed
US-5045593-A Adducts of Phosphatides and Anionic or Cationic Addition Polymers, Fluid Loss Control Agents, Well Drilling Fluids VENTURE CHEMICALS, INC. (US) 1991-09-03 US disclosed
US-4956104-A OIL WELL FLUIDS, ADDUCT OF A POLYMER AND ONE OR MORE PHOSPHATIDES VENTURE CHEMICALS, INC. (US) 1990-09-11 US disclosed
US-4863980-A ADDUCT OF POLYSACCHARIDES AND PHOSPHATIDES VENTURE CHEMICALS, INC. (US) 1989-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301299-A1 DISINFECTING FORMULATIONS WITH CARVACROL SMURF1, CACNG5, WASHC5 ALDH1A1 2684/4885CA2 2149/4885CA1 2348/4885
US-20090264431-A1 NOVEL CATHEPSIN C INHIBITORS AND THEIR USE CTSB, CTSS, CTSF ALDH1A1 2060/4885CA2 212/4885CA1 1144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.