Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77032 | 0.79 | KMT2A (0.68) | NPC1RAB9AKDM4EKMT2AMAPT | |
| SCHEMBL6773815 | 0.79 | MEN1 (0.57) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL12343965 | 0.77 | NPC1 (0.55) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL5221465 | 0.72 | PDPK1 (0.54) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL23300711 | 0.71 | LIMK1 (0.44) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL2091652 | 0.71 | ALDH1A1 (0.53) | NPSR1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL398871 | 0.71 | MIF (0.51) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL397884 | 0.69 | ALDH1A1 (0.65) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL2960850 | 0.68 | MIF (0.52) | NPC1RAB9ANPSR1KDM4EKMT2A | |
| SCHEMBL4775819 | 0.68 | TAS1R3 (0.44) | KDM4EKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063987-A1 | Method for producing alkoxymalononitriles | BARTEK JOHANNES (CH) | 2004-04-01 | — | — | US | disclosed |
| US-6673957-B2 | DEHYDRATION OF ALKOXY MALONIC ACID DIAMIDES | LONZA AG (CH) | 2004-01-06 | — | — | US | disclosed |
| US-20030144538-A1 | Method for producing alkoxy malonic acid dinitriles | LONZA AG (CH) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063987-A1 | Method for producing alkoxymalononitriles | AQP1, KCNH1, CNOT1 | NPC1 1528/4885RAB9A 2377/4885NPSR1 2718/4885 |
| US-20030144538-A1 | Method for producing alkoxy malonic acid dinitriles | ME1, ADH1C, CA6 | NPC1 2881/4885RAB9A 1622/4885NPSR1 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.