Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448077 | 0.93 | KDM4E (0.54) | KDM4ETAAR1CTSKCTSSKMT2A | |
| SCHEMBL6449654 | 0.90 | CTSK (0.56) | KDM4ETAAR1CTSKCTSSKMT2A | |
| SCHEMBL6447527 | 0.88 | LMNA (0.41) | KDM4ECTSKCTSSCNR1CNR2 | |
| SCHEMBL6443745 | 0.87 | CTSS (0.47) | CTSKCTSSCNR1CNR2GAA | |
| SCHEMBL6446969 | 0.86 | KDM4E (0.44) | KDM4ETAAR1CTSKCTSSKMT2A | |
| SCHEMBL6445664 | 0.85 | ALDH1A1 (0.45) | KDM4ECTSKCTSSKMT2AALDH1A1 | |
| SCHEMBL6442268 | 0.82 | KDM4E (0.58) | KDM4ETAAR1CTSKCTSSKMT2A | |
| SCHEMBL6443471 | 0.82 | RAB9A (0.46) | KDM4ETAAR1CTSKCTSSKMT2A | |
| SCHEMBL6443588 | 0.80 | NPC1 (0.51) | CTSKCTSSGAACTSL | |
| SCHEMBL6472461 | 0.79 | CTSD (0.46) | CTSKCTSSKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |