SCHEMBL6840443

SCHEMBL6840443

CCc1ccc(-c2ccccn2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
CYP2D6 P10635 1/20 0.59
CYP19A1 P11511 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 5/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31211649 1.00 CYP1A2 (0.59) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL31400240 0.89 CYP1A2 (0.49) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL21988536 0.89 CYP1A2 (0.49) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL26553101 0.87 CYP1A2 (0.48) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL26556299 0.87 CYP1A2 (0.48) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL28426269 0.86 CYP1A2 (0.46) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL31039983 0.85 CYP1A2 (0.45) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL3177333 0.85 CYP1A2 (0.60) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL19010901 0.84 TP53 (0.60) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL18466596 0.83 CYP1A2 (0.58) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10151699-B2 Development of lead ion testing paper with naked-eye observable readout for ten min on-site detection HONG KONG BAPTIST UNIVERSITY (HK) 2018-12-11 US claimed
US-10145825-B2 Luminescent Iridium(III) complex and its uses thereof for the G-quadruplex-based switch-on rapid detection of lead ions HONG KONG BAPTIST UNIVERSITY (HK) 2018-12-04 US claimed
US-20170102330-A1 Development of lead ion testing paper with naked-eye observable readout for ten min on-site detection UNIVERSITY OF MACAU (MO) 2017-04-13 US claimed
US-20170102331-A1 Luminescent Iridium(III) complex and its uses thereof for the G-quadruplex-based switch-on rapid detection of lead ions HONG KONG BAPTIST UNIVERSITY (HK) 2017-04-13 US claimed
CN-101538289-B Monomer for organic electro-phosphorescent polymer XIAN MODERN CHEMISTRY RES INST 2011-09-28 CN claimed
CN-101538289-A Monomer for organic electro-phosphorescent polymer XIAN MODERN CHEMISTRY RES INST 2009-09-23 CN claimed
US-20230365582-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY ON PROSTAGLANDIN E2 RECEPTOR AND USES THEREOF KANAPH THERAPEUTICS INC. (KR) 2023-11-16 US disclosed
US-20230365582-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY ON PROSTAGLANDIN E2 RECEPTOR AND USES THEREOF KANAPH THERAPEUTICS INC. (KR) 2023-11-16 US disclosed
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors Lilac Therapeutics, Inc. (US) 2023-11-07 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
EP-4201404-A1 ANTIVIRAL COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION Erasmus University Rotterdam Medical Center (NL) 2023-06-28 EP disclosed
US-20070167476-A1 Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 US disclosed
US-20070167476-A1 Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 US disclosed
US-7192918-B2 Tripeptide and tetrapeptide sulfones TELIK, INC. (US) 2007-03-20 US disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method CHENG PETER T 2007-01-18 US disclosed
US-20050159469-A1 HIV protease inhibiting compounds ABBVIE INC. 2005-07-21 US disclosed
US-20050148623-A1 Prevent reproduct of aids virus ABBVIE INC. 2005-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 CYP1A2 2689/4885CYP2D6 1595/4885CYP19A1 2120/4885
US-20050148623-A1 Prevent reproduct of aids virus SERPINB1, PRSS1, SERPINA3 CYP1A2 920/4885CYP2D6 1068/4885CYP19A1 52/4885
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors UGDH, PGD, PNPO CYP1A2 514/4885CYP2D6 375/4885CYP19A1 1204/4885
US-20070167476-A1 Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds IL4, IL2, IL5 CYP1A2 1717/4885CYP2D6 2853/4885CYP19A1 2398/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 CYP1A2 1490/4885CYP2D6 2724/4885CYP19A1 2219/4885
US-20230365582-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY ON PROSTAGLANDIN E2 RECEPTOR AND USES THEREOF PTGER1, PTGIR, PTGDR2 CYP1A2 747/4885CYP2D6 845/4885CYP19A1 304/4885
US-20050159469-A1 HIV protease inhibiting compounds SERPINB1, HPN, DNPEP CYP1A2 2459/4885CYP2D6 1947/4885CYP19A1 1299/4885
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method GPR119, LIPC, ACACA CYP1A2 1181/4885CYP2D6 1134/4885CYP19A1 657/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 CYP1A2 2224/4885CYP2D6 2100/4885CYP19A1 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.