SCHEMBL685867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685750	0.85	KMT2A (0.37)	KMT2AMAPTPOLBHPGDPARP10
	SCHEMBL19203888	0.83	MAPT (0.51)	KMT2AMAPTPOLBHPGDPARP10
	SCHEMBL6689051	0.82	KMT2A (0.35)	KMT2AMAPTPOLBPARP10NPSR1
	SCHEMBL6694487	0.82	TSHR (0.37)	KMT2AMAPTLMNAMAPK1GAA
	SCHEMBL6689348	0.80	KMT2A (0.41)	KMT2AMAPTPOLBHPGDPARP10
	SCHEMBL6693121	0.80	TP53 (0.42)	MAPTLMNAPPARGPPARAGAA
	SCHEMBL6691353	0.78	TP53 (0.44)	MAPTLMNAPPARGPPARAGAA
	SCHEMBL6691528	0.77	KMT2A (0.43)	KMT2AMAPTPOLBHPGDPARP10
	SCHEMBL12058280	0.77	LTB4R (0.32)	KMT2AMAPTPOLBHPGDXBP1
	SCHEMBL9626832	0.77	MAPT (0.44)	KMT2AMAPTPOLBHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.