Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293117 | 0.89 | LMNA (0.33) | — | |
| Water SCHEMBL28800260 | 0.87 | KDM4E (0.30) | — | |
| SCHEMBL62393 | 0.87 | KDM4E (0.32) | — | |
| Potassium Ion SCHEMBL5383247 | 0.84 | LMNA (0.33) | — | |
| SCHEMBL987341 | 0.80 | SIGMAR1 (0.30) | — | |
| SCHEMBL6261605 | 0.78 | POLB (0.32) | TSHR | |
| SCHEMBL6542902 | 0.78 | — | — | |
| SCHEMBL28122578 | 0.78 | FDPS (0.34) | ALDH1A1 | |
| SCHEMBL10781958 | 0.76 | CHRM2 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL5047965 | 0.76 | FDPS (0.38) | ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1563822-B1 | Dental material based on alkoxysilyl functional polyether comprising a catalyst | KETTENBACH GMBH & CO KG (DE) | 2020-09-02 | — | — | EP | claimed |
| US-6821761-B2 | CEREBROSIDES/GANGLIOSIDES; DERIVED FROM PSEUDOMONAS OR SHEWANELLA | TAKARA BIO, INC. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030166250-A1 | Sphingolpid ceramide N-deacylase, methods for producing sphingolipids and sphingolipid derivatives, and sphingolipid ceramide N-deacylase gene | TAKARA SHUZO CO., LTD. | 2003-09-04 | — | — | US | disclosed |
| US-6428999-B1 | USEFUL IN MEDICINE, CARBOHYDRATE ENGINEERING, CELL ENGINEERING | TAKARA SHUZO CO., LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| US-20020086410-A1 | SPHINGOLIPID CERAMIDE N-DEACYLASE, METHODS FOR PRODUCING SPHINGOLIPIDS AND SPHINGOLIPID DERIVATIVES, AND SPHINGOLIPID CERAMIDE N-DEACYLASE GENE | TAKARA SHUZO CO., LTD. (JP) | 2002-07-04 | — | — | US | disclosed |
| US-3960840-A | Fluorescent derivatives of adenine-containing compounds | UNIVERSITY OF ILLINOIS FOUNDATON (US) | 1976-06-01 | — | — | US | disclosed |