Tiviciclovir

Tiviciclovir

SCHEMBL6944256

Nc1nc2c(ncn2CC(CO)CO)c(=O)[nH]1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.67
MEN1 O00255 1/20 0.67
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.67
CYP3A4 P08684 1/20 0.67
NFKB1 P19838 1/20 0.67
VCP P55072 1/20 0.67
KMT2A Q03164 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HIF1A Q16665 1/20 0.67
HPRT1 P00492 12/20 0.66
TK1 P04183 2/20 0.64
PNP P00491 2/20 0.63
USP2 O75604 1/20 0.63
TSHR P16473 1/20 0.63
EDNRA P25101 1/20 0.63
HTR2A P28223 1/20 0.63
RECQL P46063 1/20 0.63
HBB P68871 1/20 0.63
HSD17B10 Q99714 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiviciclovir SCHEMBL7745021 0.99 BLM (0.66) BLMMEN1ALDH1A1LMNACYP3A4
Omaciclovir SCHEMBL417577 0.92 TK1 (0.62) BLMMEN1ALDH1A1LMNACYP3A4
Omaciclovir SCHEMBL712427 0.92 TK1 (0.62) BLMMEN1ALDH1A1LMNACYP3A4
Omaciclovir SCHEMBL10507800 0.91 TK1 (0.61) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL10506595 0.90 TK1 (0.65) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL9172592 0.89 HPRT1 (0.70) BLMMEN1ALDH1A1LMNACYP3A4
Omaciclovir SCHEMBL571367 0.88 HPRT1 (0.66) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL23710631 0.88 HPRT1 (0.67) BLMMEN1ALDH1A1LMNACYP3A4
Penciclovir SCHEMBL3495 0.88 TK1 (0.70) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL24420506 0.88 HPRT1 (0.67) BLMMEN1ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948332-B1 ANTIHERPETIC MEDICATED STICK CONTAINING ACYCLOVIR FOR TOPICAL APPLICATION RECORDATI CHEM PHARM (CH) 2003-09-03 EP claimed
EP-1019404-A4 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMW SCIENT IND RES ORG (AU) 2001-07-04 EP claimed
EP-1019404-A1 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-07-19 EP claimed
EP-0948332-A1 ANTIHERPETIC PHARMACEUTICAL COMPOSITIONS CONTAINING ACYCLOVIR FOR TOPICAL APPLICATORS RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1999-10-13 EP claimed
WO-1999012927-A1 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-03-18 WO claimed
WO-1998018472-A1 ANTIHERPETIC PHARMACEUTICAL COMPOSITIONS CONTAINING ACYCLOVIR FOR TOPICAL APPLICATORS RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1998-05-07 WO claimed
US-20250387363-A1 LIQUID EPINEPHRINE PRODRUG FORMULATIONS AND LIQUID EPINEPHRINE FORMULATIONS INSIGNIS THERAPEUTICS INC (US) 2025-12-25 US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20250000821-A1 METHODS OF USING DIPIVEFRIN Insignis Therapeutics, Inc. 2025-01-02 US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
CN-111565716-B Method of using dipivefrin 因斯格尼斯疗法有限公司 2023-06-09 CN disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-20100298256-A1 ANTIVIRAL COMPOUNDS EPIPHANY BIOSCIENCES, INC. 2010-11-25 US disclosed
US-20100298256-A1 ANTIVIRAL COMPOUNDS EPIPHANY BIOSCIENCES, INC. 2010-11-25 US disclosed
WO-2009085267-A1 ANTIVIRAL COMPOUNDS EPIPHANY BIOSCIENCES (US) 2009-07-09 WO disclosed
EP-1019404-A4 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMW SCIENT IND RES ORG (AU) 2001-07-04 EP disclosed
EP-1019404-A1 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-07-19 EP disclosed
WO-1999012927-A1 PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000821-A1 METHODS OF USING DIPIVEFRIN QDPR, DNPEP, DPEP1 BLM 1124/4885MEN1 419/4885ALDH1A1 1423/4885
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 BLM 595/4885MEN1 4821/4885ALDH1A1 1053/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 BLM 811/4885MEN1 2694/4885ALDH1A1 72/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 BLM 811/4885MEN1 2694/4885ALDH1A1 72/4885
US-20100298256-A1 ANTIVIRAL COMPOUNDS MTAP, PNP, TYMP BLM 1852/4885MEN1 3239/4885ALDH1A1 1707/4885
US-20250387363-A1 LIQUID EPINEPHRINE PRODRUG FORMULATIONS AND LIQUID EPINEPHRINE FORMULATIONS ADRB3, ADRB2, ADRB1 BLM 1987/4885MEN1 1013/4885ALDH1A1 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.