Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135809 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL17693406 | 0.89 | ALDH1A1 (0.57) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL14060191 | 0.87 | SMN1; SMN2 (0.44) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL1664842 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2900095 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL25207012 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2894583 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2899979 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL14715643 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2896615 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830916-B | Preparation method of 2, 5-furandicarboxylic acid under mild condition | 中国科学院宁波材料技术与工程研究所 | 2021-08-13 | — | — | CN | claimed |
| CN-117619441-A | Difunctional carbon-based solid acid catalyst, preparation method and application | 淮阴师范学院 | 2024-03-01 | — | — | CN | disclosed |
| US-11655227-B2 | Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant | EASTMAN CHEMICAL COMPANY (US) | 2023-05-23 | — | — | US | disclosed |
| US-11655227-B2 | Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant | EASTMAN CHEMICAL COMPANY (US) | 2023-05-23 | — | — | US | disclosed |
| US-10882032-B2 | Furan-2,5-dicarboxylic acid purge process | EASTMAN CHEMICAL COMPANY (US) | 2021-01-05 | — | — | US | disclosed |
| US-10875834-B2 | Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2020-12-29 | — | — | US | disclosed |
| US-10875834-B2 | Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2020-12-29 | — | — | US | disclosed |
| CN-107501215-B | Method and device for continuously preparing 5-hydroxymethylfurfural and derivatives thereof | 中国农业大学 | 2020-10-30 | — | — | CN | disclosed |
| US-20200331879-A1 | METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE | EASTMAN CHEMICAL COMPANY (US) | 2020-10-22 | — | — | US | disclosed |
| US-10723712-B2 | Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant | EASTMAN CHEMICAL COMPANY (US) | 2020-07-28 | — | — | US | disclosed |
| US-20120302769-A1 | OXIDATION PROCESS TO PRODUCE A CRUDE AND/OR PURIFIED CARBOXYLIC ACID PRODUCT | EASTMAN CHEMICAL COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-8242293-B2 | Method for the synthesis of organic acid esters of 5-hydroxymethylfurfural and their use | FURANIX TECHNOLOGIES B.V. (NL) | 2012-08-14 | — | — | US | disclosed |
| EP-2423205-A1 | Conversion of carbohydrates to hydroxymethylfurfural (HMF) and derivatives | Archer-Daniels-Midland Company (US) | 2012-02-29 | — | — | EP | disclosed |
| CN-101896476-A | Conversion of carbohydrates to Hydroxymethylfurfural (HMF) and derivatives | ARCHER DANIELS MIDLAND CO | 2010-11-24 | — | — | CN | disclosed |
| EP-2217584-A2 | CONVERSION OF CARBOHYDRATES TO HYDROXY-METHYLFURFURAL (HMF) AND DERIVATIVES | Archer Daniels Midland Company (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090306415-A1 | Method For The Synthesis Of Organic Acid Esters Of 5-Hydroxymethylfurfural And Their Use | FURANIX TECHNOLOGIES B.V. (NL) | 2009-12-10 | — | — | US | disclosed |
| WO-2009076627-A2 | CONVERSION OF CARBOHYDRATES TO HYDROXY-METHYLFURFURAL (HMF) AND DERIVATIVES | ARCHER DANIELS MIDLAND CO (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20090156841-A1 | CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES | ARCHER DANIELS MIDLAND CO. | 2009-06-18 | — | — | US | disclosed |
| EP-2001859-A1 | METHOD FOR THE SYNTHESIS OF ORGANIC ACID ESTERS OF 5-HYDROXYMETHYLFURFURAL AND THEIR USE | Furanix Technologies B.V (NL) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007104515-A1 | METHOD FOR THE SYNTHESIS OF ORGANIC ACID ESTERS OF 5-HYDROXYMETHYLFURFURAL AND THEIR USE | FURANIX TECHNOLOGIES B.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875834-B2 | Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives | MTHFD1, MTHFD2, ADH5 | ALDH1A1 27/4885TSHR 2756/4885SMN1; SMN2 384/4885 |
| US-10882032-B2 | Furan-2,5-dicarboxylic acid purge process | DDC, PCCA, DPYD | ALDH1A1 197/4885TSHR 4372/4885SMN1; SMN2 3059/4885 |
| US-20200331879-A1 | METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE | DDC, ACACA, ACACB | ALDH1A1 198/4885TSHR 3693/4885SMN1; SMN2 2932/4885 |
| US-20090156841-A1 | CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES | HPD, FOS, MCCC2 | ALDH1A1 953/4885TSHR 3037/4885SMN1; SMN2 1252/4885 |
| US-10723712-B2 | Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant | DDC, DLAT, FDFT1 | ALDH1A1 127/4885TSHR 3251/4885SMN1; SMN2 4665/4885 |
| US-20120302769-A1 | OXIDATION PROCESS TO PRODUCE A CRUDE AND/OR PURIFIED CARBOXYLIC ACID PRODUCT | PCCA, ODC1, DDO | ALDH1A1 113/4885TSHR 4153/4885SMN1; SMN2 3051/4885 |
| US-11655227-B2 | Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant | DDC, DLAT, FDFT1 | ALDH1A1 127/4885TSHR 3251/4885SMN1; SMN2 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.