Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986313 | 0.81 | KDM4E (0.53) | HTR6DRD2 | |
| SCHEMBL6976687 | 0.79 | KCNH2 (0.39) | HTR6DRD2KCNH2 | |
| SCHEMBL6985174 | 0.74 | HTR6 (0.39) | HTR6HTR7DRD2HPGDKCNH2 | |
| SCHEMBL6983492 | 0.73 | CHRNA7 (0.40) | HTR7DRD2KCNH2 | |
| SCHEMBL6162425 | 0.70 | HTR6 (0.67) | HTR6HTR7DRD2 | |
| Hydrochloric Acid SCHEMBL6984760 | 0.69 | DRD2 (0.40) | HTR7DRD2 | |
| SCHEMBL8450188 | 0.68 | HTR7 (0.44) | HTR6HTR7DRD2HPGD | |
| SCHEMBL8578232 | 0.67 | SIGMAR1 (0.46) | — | |
| SCHEMBL8573871 | 0.66 | LMNA (0.42) | — | |
| Hydrochloric Acid SCHEMBL6981674 | 0.64 | SIGMAR1 (0.38) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |