Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS8 | Q16651 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062828 | 0.80 | PRSS8 (0.43) | PRSS8ELANECA1ATMCTSS | |
| SCHEMBL7042854 | 0.78 | PRSS8 (0.49) | PRSS8ELANECTSSCYP3A4CYP2C9 | |
| SCHEMBL7045318 | 0.77 | CTSS (0.45) | PRSS8CTSSCYP3A4CYP2C9CTSL | |
| SCHEMBL7415173 | 0.74 | PRSS8 (0.41) | PRSS8ELANECA1ATMCTSS | |
| SCHEMBL7415176 | 0.73 | ELANE (0.44) | PRSS8ELANEATMCTSSCYP3A4 | |
| SCHEMBL7045289 | 0.71 | PRSS8 (0.45) | PRSS8ELANECA1ATMCTSS | |
| SCHEMBL7136742 | 0.71 | PORCN (0.40) | CA1CTSSCYP3A4CA2CTSL | |
| SCHEMBL6466347 | 0.69 | CTSK (0.58) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6465885 | 0.69 | XDH (0.47) | PRSS8ELANECTSSCTSLCTSB | |
| SCHEMBL7046460 | 0.69 | PRSS8 (0.47) | PRSS8ELANECTSSCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | PRSS8 33/4885ELANE 50/4885CA1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.