Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373022 | 0.79 | ADH1B (0.42) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL7061205 | 0.77 | RAB9A (0.40) | ALDH1A1HTT | |
| SCHEMBL5767016 | 0.75 | MMP8 (0.39) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL7059655 | 0.74 | TSHR (0.41) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL28754827 | 0.72 | CETP (0.33) | CNR2ALOX5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7064438 | 0.72 | CYP1A2 (0.49) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL5767277 | 0.71 | ESR1 (0.41) | — | |
| SCHEMBL6762362 | 0.68 | RIPK1 (0.37) | ALDH1A1MEN1KMT2AHPGDALOX5 | |
| SCHEMBL7061210 | 0.68 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7062957 | 0.67 | CYP2A6 (0.50) | FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162783-A1 | Method and composition for the treatment of pain | ASTRAZENECA AB (SE) | 2003-08-28 | — | — | US | disclosed |
| EP-1248621-A1 | METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001047523-A1 | METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162783-A1 | Method and composition for the treatment of pain | OPRK1, OPRD1, ACHE | FAAH 45/4885ALDH1A1 170/4885MEN1 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.