Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069983 | 0.84 | LMNA (0.58) | ALDH1A1MAPTLMNAPKML3MBTL1 | |
| SCHEMBL7069936 | 0.82 | SMN1; SMN2 (0.60) | ALDH1A1MAPTGAALMNATHRB | |
| SCHEMBL7069907 | 0.81 | VCAM1 (0.52) | MAPTLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL8080659 | 0.81 | LMNA (0.55) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL7073993 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAKMT2AMEN1MGLL | |
| SCHEMBL7074280 | 0.79 | LMNA (0.57) | GAAMAPK1LMNATHRBKMT2A | |
| SCHEMBL7074464 | 0.78 | POLB (0.59) | MAPTGAAMAPK1LMNATHRB | |
| SCHEMBL7074158 | 0.78 | MEN1 (0.68) | ALDH1A1MAPTGAALMNATHRB | |
| SCHEMBL7075338 | 0.77 | THRB (0.58) | ALDH1A1MAPTMAPK1LMNATHRB | |
| SCHEMBL8073643 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |