SCHEMBL716072

SCHEMBL716072

CCOCCCS(=O)(=O)[O-].[Na+]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
THPO P40225 1/20 0.44
HBB P68871 1/20 0.44
PMP22 Q01453 1/20 0.44
BBOX1 O75936 3/20 0.42
HPGD P15428 3/20 0.38
RECQL P46063 2/20 0.38
EPHX2 P34913 2/20 0.38
GLA P06280 1/20 0.38
BLM P54132 1/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 4/20 0.37
MAPT P10636 2/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19640303 0.85 TSHR (0.52) TSHRALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL6730611 0.84 TSHR (0.45) TSHRALDH1A1MAPK1LMNASMN1; SMN2
Potassium Ion SCHEMBL31075019 0.80 GMNN (0.46) TSHRALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL28448153 0.78 TSHR (0.48) TSHRALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL27038942 0.78 ALDH1A1 (0.38) TSHRALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL1009169 0.78 TSHR (0.50) TSHRALDH1A1MAPK1LMNASMN1; SMN2
Tetrabuthylammonium SCHEMBL1111618 0.78 RECQL (0.41) TSHRMAPK1BBOX1HPGDRECQL
SCHEMBL28077320 0.77 RECQL (0.57) TSHRALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL123320 0.77 TSHR (0.47) TSHRALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL126016 0.77 TSHR (0.47) TSHRALDH1A1MAPK1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024237073-A1 SILICA FINE PARTICLE DISPERSION FOR POLISHING, COMPOSITION FOR POLISHING, AND METHOD FOR PRODUCING SILICA FINE PARTICLE DISPERSION FOR POLISHING 日揮触媒化成株式会社 2024-11-21 WO disclosed
US-11891307-B2 Silica-based particle dispersion and production method therefor JGC CATALYSTS AND CHEMICALS LTD. (JP) 2024-02-06 US disclosed
CN-109155246-B Silica-based composite microparticle dispersion and process for producing the same 日挥触媒化成株式会社 2024-01-05 CN disclosed
EP-3539926-B1 CERIA COMPOSITE PARTICLE DISPERSION, METHOD FOR PRODUCING SAME, AND POLISHING ABRASIVE GRAIN DISPERSION COMPRISING CERIA COMPOSITE PARTICLE DISPERSION JGC CATALYSTS & CHEMICALS LTD (JP) 2023-07-12 EP disclosed
EP-3447790-B1 SILICA-BASED COMPOSITE FINE PARTICLE DISPERSION AND METHOD FOR MANUFACTURING SAME JGC CATALYSTS & CHEMICALS LTD (JP) 2023-05-24 EP disclosed
CN-109937187-B Cerium oxide-based composite microparticle dispersion, method for producing same, and abrasive particle dispersion for polishing containing cerium oxide-based composite microparticle dispersion 日挥触媒化成株式会社 2022-08-09 CN disclosed
US-20220055908-A1 SILICA-BASED PARTICLE DISPERSION AND PRODUCTION METHOD THEREFOR JGC CATALYSTS AND CHEMICALS LTD. (JP) 2022-02-24 US disclosed
US-11059997-B2 Polishing composition JGC CATALYSTS AND CHEMICALS LTD. (JP) 2021-07-13 US disclosed
US-10920120-B2 Ceria composite particle dispersion, method for producing same, and polishing abrasive grain dispersion comprising ceria composite particle dispersion JGC CATALYSTS AND CHEMICALS LTD. (JP) 2021-02-16 US disclosed
EP-3279142-B1 SILICA-BASED COMPOSITE FINE-PARTICLE DISPERSION, METHOD FOR PRODUCING SAME, AND POLISHING SLURRY INCLUDING SILICA-BASED COMPOSITE FINE-PARTICLE DISPERSION JGC CATALYSTS & CHEMICALS LTD (JP) 2021-01-06 EP disclosed
US-20060000808-A1 Polishing solution of metal and chemical mechanical polishing method FUJI PHOTO FILM CO., LTD. 2006-01-05 US disclosed
EP-1612249-A1 Polishing solution of metal and chemical mechanical polishing method FUJI PHOTO FILM CO., LTD. (JP) 2006-01-04 EP disclosed
US-20050191823-A1 Polishing composition and polishing method FUJIMI INCORPORATED (JP) 2005-09-01 US disclosed
EP-1568746-A1 Polishing composition and polishing method FUJIMI INCORPORATED (JP) 2005-08-31 EP disclosed
US-6899821-B2 Abrasive liquid for metal and method for polishing HITACHI CHEMICAL COMPANY, LTD. (JP) 2005-05-31 US disclosed
US-6896825-B1 Abrasive liquid for metal and method for polishing HITACHI CHEMICAL COMPANY, LTD (JP) 2005-05-24 US disclosed
US-20050095860-A1 Abrasive liquid for metal and method for polishing RENESAS ELECTRONICS CORPORATION (JP) 2005-05-05 US disclosed
US-20020017630-A1 Abrasive liquid for metal and method for polishing RENESAS ELECTRONICS CORPORATION (JP) 2002-02-14 US disclosed
EP-1150341-A1 MATERIALS FOR POLISHING LIQUID FOR METAL, POLISHING LIQUID FOR METAL, METHOD FOR PREPARATION THEREOF AND POLISHING METHOD USING THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2001-10-31 EP disclosed
EP-1137056-A1 ABRASIVE LIQUID FOR METAL AND METHOD FOR POLISHING HITACHI CHEMICAL COMPANY, LTD. (JP) 2001-09-26 EP disclosed