Phthalic Acid

Phthalic Acid

SCHEMBL589207

O=C([O-])c1ccccc1C(=O)O.O=C([O-])c1ccccc1C(=O)O.[Na+].[Na+]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.54
CA4 known ✓ P22748 2/20 0.54
CA12 known ✓ O43570 1/20 0.52
CA1 known ✓ P00915 1/20 0.52
ALDH1A1 P00352 5/20 0.70
ALOX15 P16050 1/20 0.70
KDM4E B2RXH2 2/20 0.60
HPGD P15428 2/20 0.60
AKR1C3 P42330 3/20 0.54
HMGB1 P09429 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
POLB P06746 1/20 0.48
CDC25B P30305 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL7030041 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL29098715 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL29098719 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL29098718 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL7030044 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL29726051 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL29098716 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL192153 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL3922241 0.98 ALDH1A1 (0.67) ALDH1A1ALOX15KDM4EHPGDCA2
Phthalic Acid SCHEMBL30634898 0.98 ALDH1A1 (0.67) ALDH1A1ALOX15KDM4EHPGDCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12529628-B2 Microbeads and preparation method therefor LG CHEM, LTD. (KR) 2026-01-20 US claimed
CN-116516433-B Green rapid preparation method of metal organic framework compound film coating 中国科学院深圳先进技术研究院 2024-04-26 CN claimed
CN-116516433-A Green rapid preparation method of metal organic framework compound film coating 中国科学院深圳先进技术研究院 2023-08-01 CN claimed
WO-2023138283-A1 ENVIRONMENTALLY FRIENDLY AND RAPID PREPARATION METHOD FOR METAL-ORGANIC FRAMEWORK COMPOUND THIN FILM PLATING 中国科学院深圳先进技术研究院 2023-07-27 WO claimed
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-18 US claimed
US-20180327550-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2018-11-15 US claimed
EP-3377560-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF University of Maryland, College Park (US) 2018-09-26 EP claimed
US-20130184499-A1 PREPARATION OF CATALYST FOR SELECTIVE HYDROGENATION OF HYDROGENATABLE PRECURSORS BIOAMBER INTERNATIONAL S.A.R.L. (LU) 2013-07-18 US claimed
WO-2013106519-A1 PREPARATION OF CATALYST FOR SELECTIVE HYDROGENATION OF HYDROGENATABLE PRECURSORS BIOAMBER INTERNATIONAL S.A.R.L. (LU) 2013-07-18 WO claimed
US-20260077088-A1 SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES CRANNMED LIMITED (IE) 2026-03-19 US disclosed
US-20260053152-A1 COMPOSITIONS AND METHODS OF TREATING EDIBLE MATTER AND SUBSTRATES THEREFOR SAVE FOODS LTD. (IL) 2026-02-26 US disclosed
US-12529628-B2 Microbeads and preparation method therefor LG CHEM, LTD. (KR) 2026-01-20 US disclosed
US-12527331-B2 Compositions and methods of treating edible matter and substrates therefor SAVE FOODS LTD. (IL) 2026-01-20 US disclosed
US-12465600-B2 Pediatric suspension formulation Xeolas Pharmaceuticals Ltd. (IE) 2025-11-11 US disclosed
EP-1885333-B1 PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION AMARIN PHARMACEUTICALS IE LTD (IE) 2012-02-15 EP disclosed
US-20090023766-A1 Pharmaceutical formulation of apomorphine for buccal administration AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2009-01-22 US disclosed
EP-1885333-A1 PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION Amarin Pharmaceuticals Ireland Limited (IE) 2008-02-13 EP disclosed
WO-2006120412-A1 PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2006-11-16 WO disclosed
US-20050227225-A1 Stabilization of biomolecules in samples ROCHE MOLECULAR SYSTEMS, INC. (US) 2005-10-13 US disclosed
EP-1584923-A2 Stabilization of biomolecules in samples Roche Diagnostics GmbH (DE) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180327550-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF PHOSPHO1, PLCG2, PLCG1 CA2 384/4885CA4 217/4885CA12 154/4885
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof PHOSPHO1, PLCG2, PLCG1 CA2 384/4885CA4 217/4885CA12 154/4885
US-20260053152-A1 COMPOSITIONS AND METHODS OF TREATING EDIBLE MATTER AND SUBSTRATES THEREFOR SOAT2, AGL, SOAT1 CA2 167/4885CA4 1341/4885CA12 623/4885
US-12527331-B2 Compositions and methods of treating edible matter and substrates therefor AGL, SOAT2, SOAT1 CA2 137/4885CA4 1042/4885CA12 581/4885
US-20090023766-A1 Pharmaceutical formulation of apomorphine for buccal administration PARK7, SNCA, AMY2A CA2 1164/4885CA4 2781/4885CA12 1787/4885
US-20260077088-A1 SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES MMP2, PLG, PMM2 CA2 234/4885CA4 402/4885CA12 273/4885
US-12529628-B2 Microbeads and preparation method therefor SLC6A11, SLC16A7, SLC5A11 CA2 9/4885CA4 62/4885CA12 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.