Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401588 | 0.87 | NAALAD2 (0.42) | CA2KMT2AFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL7364668 | 0.85 | ANPEP (0.37) | KMT2AFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL7399249 | 0.85 | GABBR2 (0.39) | KMT2AFFAR1HSD11B1CYP1A2SLC6A9 | |
| SCHEMBL7396691 | 0.85 | TSHR (0.36) | KMT2AFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL7366777 | 0.85 | HSD11B1 (0.42) | KMT2AHSD11B1PTGFRALDH1A1CYP1A2 | |
| SCHEMBL7400114 | 0.85 | SLC6A9 (0.41) | FFAR1PTGFRGRIK2ALDH1A1CYP1A2 | |
| SCHEMBL7367347 | 0.79 | GRM2 (0.37) | KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7367032 | 0.79 | ALDH1A1 (0.36) | FFAR1PTGFRALDH1A1CYP1A2RAB9A | |
| SCHEMBL7364859 | 0.77 | ANPEP (0.43) | CA1CA2GRIK2ALDH1A1CYP1A2 | |
| SCHEMBL7365727 | 0.77 | SLC6A9 (0.41) | FFAR1L3MBTL1ALDH1A1CYP1A2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |