SCHEMBL738555

SCHEMBL738555

N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.67
SLC7A5 Q01650 3/20 0.62
PTGS1 P23219 2/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
XIAP P98170 1/20 0.61
PTPN1 P18031 1/20 0.60
ALOX15 P16050 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 1/20 0.56
CYP2C19 P33261 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPK1 P28482 1/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
EGFR P00533 1/20 0.53
LCK P06239 1/20 0.53
FYN P06241 1/20 0.53
ADORA3 P0DMS8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL738554 1.00 PTPRC (0.67) PTPRCSLC7A5PTGS1ALPIPKM
SCHEMBL12501710 1.00 PTPRC (0.67) PTPRCSLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL9556543 0.98 PTPRC (0.65) PTPRCSLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL9556546 0.98 PTPRC (0.65) PTPRCSLC7A5PTGS1ALPIPKM
Butylamine SCHEMBL6354985 0.87 PTPRC (0.53) PTPRCSLC7A5PTGS1ALPIPKM
SCHEMBL14317337 0.86 PTPRC (0.50) PTPRCSLC7A5PTPN1
SCHEMBL2310526 0.84 SLC7A5 (0.83) PTPRCSLC7A5PTGS1ALPIPKM
SCHEMBL6021374 0.83 MAPK1 (0.66) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL499205 0.83 MAPK1 (0.66) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL215652 0.83 PTPRC (0.56) PTPRCSLC7A5PTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
CN-119060630-A Single-component water-based high-temperature-resistant paint with temperature spraying function and preparation method thereof 河北比尔尼克新材料科技股份有限公司 2024-12-03 CN claimed
US-20230220007-A1 SETD7 EPIGENETIC MODULATORS BIORCHESTRA CO., LTD. (KR) 2023-07-13 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
WO-2021209930-A1 SETD7 EPIGENETIC MODULATORS BIORCHESTRA CO., LTD. (KR) 2021-10-21 WO claimed
US-20210032304-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2021-02-04 US claimed
EP-3752174-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF University of Florida Research Foundation, Incorporated (US) 2020-12-23 EP claimed
CN-111936157-A Fibroblast growth factor analogs and uses thereof 佛罗里达大学研究基金会 2020-11-13 CN claimed
US-20140057877-A1 Therapeutic polyamine compositions and their synthesis MURPHY MICHAEL A (US) 2014-02-27 US claimed
EP-2673381-A2 BIOPROBES AND METHODS OF USE THEREOF The Governing Council Of The University Of Toronto (CA) 2013-12-18 EP claimed
WO-2012109157-A2 BIOPROBES AND METHODS OF USE THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2012-08-16 WO claimed
US-20090030181-A1 Peptides for Inhibiting MDM2 Function KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KP) 2009-01-29 US claimed
JP-2006502081-A 2006-01-19 JP claimed
WO-2005097820-A1 PEPTIDES FOR INHIBITING MDM2 FUNCTION KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2005-10-20 WO claimed
US-20050085555-A1 Composition, synthesis and therapeutic applications of polyamines MURPHY, MICHAEL A. 2005-04-21 US claimed
EP-1465611-A2 COMPOSITION, SYNTHESIS AND THERAPEUTIC APPLICATIONS OF POLYAMINES Murphy, Michael A. (US) 2004-10-13 EP claimed
WO-2003051348-A2 COMPOSITION, SYNTHESIS AND THERAPEUTIC APPLICATIONS OF POLYAMINES MURPHY MICHAEL A (US) 2003-06-26 WO claimed
US-6307090-B1 OXALYL ENDCAPPED; CONTAINING A BIVALENT RADICAL OF PHOSPHOTYROSINE OR A PHOSPHOTYROSINE MIMETIC THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2001-10-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM PTPRC 2241/4885SLC7A5 1166/4885PTGS1 2925/4885
US-20230220007-A1 SETD7 EPIGENETIC MODULATORS SETD7, NSD1, PRMT7 PTPRC 1221/4885SLC7A5 2865/4885PTGS1 4606/4885
US-20050085555-A1 Composition, synthesis and therapeutic applications of polyamines PRDX5, PINK1, ARG2 PTPRC 437/4885SLC7A5 3319/4885PTGS1 766/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC PTPRC 3286/4885SLC7A5 378/4885PTGS1 4428/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM PTPRC 2241/4885SLC7A5 1166/4885PTGS1 2925/4885
US-20140057877-A1 Therapeutic polyamine compositions and their synthesis MCU, PC, PINK1 PTPRC 402/4885SLC7A5 3233/4885PTGS1 484/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT PTPRC 1452/4885SLC7A5 64/4885PTGS1 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.