Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436715 | 0.88 | SIGMAR1 (0.37) | POLBSIGMAR1MEN1KMT2AMAPT | |
| SCHEMBL7444723 | 0.79 | CPA3 (0.38) | ALDH1A1TSHRFKBP1ALMNAPOLB | |
| SCHEMBL7432645 | 0.75 | ENPP2 (0.47) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL7435831 | 0.73 | ACHE (0.40) | ALDH1A1TSHRPOLBACHEMEN1 | |
| SCHEMBL7426794 | 0.73 | POLB (0.37) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL7440468 | 0.72 | POLB (0.37) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL7428792 | 0.72 | CYP2D6 (0.45) | POLBKMT2ACYP2C19 | |
| SCHEMBL7445702 | 0.71 | ACHE (0.40) | ALDH1A1TSHRPOLBACHEMEN1 | |
| SCHEMBL7425893 | 0.71 | KMT2A (0.44) | ALDH1A1TSHRLMNAPOLBMEN1 | |
| SCHEMBL7438517 | 0.71 | GAA (0.35) | ALDH1A1TSHRPOLBSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |