Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562358 | 0.83 | ACKR3 (0.45) | OPRM1TMEM97SIGMAR1OPRK1SLC6A2 | |
| SCHEMBL4767101 | 0.77 | CTSD (0.37) | OPRM1SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL7430902 | 0.70 | ALDH1A1 (0.38) | SLC6A2SLC6A4ALDH1A1HPGDGAA | |
| SCHEMBL4763259 | 0.69 | CTSD (0.44) | SLC6A2SLC6A4ALDH1A1HTTMEN1 | |
| SCHEMBL6586781 | 0.68 | HTR1A (0.42) | OPRM1TMEM97SIGMAR1OPRK1SLC6A2 | |
| SCHEMBL6590690 | 0.67 | CXCR4 (0.32) | SLC6A2SLC6A4KMT2A | |
| SCHEMBL4764950 | 0.67 | CYP1A2 (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL6770905 | 0.67 | GHSR (0.38) | SLC6A2SLC6A4ATM | |
| SCHEMBL28157781 | 0.67 | ALDH1A1 (0.65) | OPRM1TMEM97SIGMAR1OPRK1ALDH1A1 | |
| SCHEMBL6633602 | 0.67 | SLC6A2 (0.40) | SLC6A2SLC6A4ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |