Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7723157

NCCC[C@@H](N)C(=O)N[C@H](CCc1ccccc1)C(O)c1nc2ccccc2s1.O=C(O)C(F)(F)F

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MMP1 P03956 1/20 0.38
FCER2 P06734 1/20 0.38
MMP2 P08253 1/20 0.38
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7723159 0.86 HDAC3 (0.35) HPGDMMP1FCER2MMP2HDAC3
Trifluoroacetic Acid SCHEMBL7734124 0.81 CYP1A2 (0.42) CYP1A2CYP2C9CYP2C19MMP2HDAC3
Trifluoroacetic Acid SCHEMBL7731111 0.81 MMP2 (0.38) MMP2HDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL7860794 0.79 MMP1 (0.39) MMP1FCER2PRSS1TPSAB1
Trifluoroacetic Acid SCHEMBL7734181 0.77 OPRK1 (0.37) MMP2CTSC
Trifluoroacetic Acid SCHEMBL7733845 0.76 LMNA (0.39) MMP2HDAC1HDAC8CTSC
SCHEMBL7723163 0.75 HPGD (0.39) HPGDCYP1A2CYP2C9CYP2C19HIF1A
Trifluoroacetic Acid SCHEMBL7731949 0.75 FAAH (0.40) HSD17B10MMP2CTSC
SCHEMBL1245537 0.75 HDAC3 (0.52) MMP1FCER2HDAC3HDAC4HDAC1
SCHEMBL7735579 0.75 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19MMP2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436980-B1 TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES ESSENTIAL THERAPEUTICS, INC. 2002-08-20 US disclosed