Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.35 |
| ▸ | GART | P22102 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7733845 | 0.90 | LMNA (0.39) | MMP2CTSCHDAC1HDAC8ERAP2 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.90 | OPRK1 (0.37) | MMP2CTSCCTSLERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.89 | CTSL (0.41) | MMP2PTPN1PTPN2CTSCCTSL | |
| Trifluoroacetic Acid SCHEMBL7731949 | 0.88 | FAAH (0.40) | MMP2FAAHCES1DAGLACTSC | |
| SCHEMBL7731113 | 0.86 | PRSS8 (0.34) | MMP2PTPN1PTPN2FAAHCES1 | |
| SCHEMBL7732452 | 0.84 | LMNA (0.42) | MMP2CTSCHDAC1HDAC8ERAP2 | |
| SCHEMBL7730106 | 0.84 | CTSC (0.38) | MMP2CTSCERAP2ERAP1LNPEP | |
| SCHEMBL7723243 | 0.84 | CTSL (0.43) | MMP2PTPN1PTPN2CTSCCTSL | |
| Trifluoroacetic Acid SCHEMBL7723157 | 0.81 | HPGD (0.39) | MMP2CTSCHDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL7734124 | 0.81 | CYP1A2 (0.42) | MMP2PTPN1DAGLAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |