Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730106 | 0.95 | CTSC (0.38) | MMP2CTSCMETAP2METAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.90 | MMP2 (0.38) | MMP2CTSCLNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.89 | CTSL (0.41) | OPRK1MMP2CTSCLNPEPERAP2 | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.89 | LMNA (0.39) | MMP2CTSCMETAP2LNPEPERAP2 | |
| Trifluoroacetic Acid SCHEMBL7735796 | 0.87 | HRH2 (0.34) | OPRK1MMP2HRH2HRH1HRH4 | |
| SCHEMBL7734185 | 0.87 | LNPEP (0.34) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7723243 | 0.85 | CTSL (0.43) | MMP2CTSCMETAP2METAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7731949 | 0.84 | FAAH (0.40) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7732452 | 0.83 | LMNA (0.42) | MMP2CTSCMETAP2LNPEPERAP2 | |
| SCHEMBL7735797 | 0.82 | METAP2 (0.32) | METAP2METAP1LNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |