Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7731111 | 0.88 | MMP2 (0.38) | FAAHDAGLACES1MMP2CTSC | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.84 | OPRK1 (0.37) | MMP2CTSCERAP2ERAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.83 | LMNA (0.39) | MMP2CTSCERAP2ERAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.81 | CTSL (0.41) | MMP2CTSCERAP2ERAP1LNPEP | |
| SCHEMBL7730106 | 0.78 | CTSC (0.38) | MMP2CTSCLTA4HERAP2ERAP1 | |
| SCHEMBL7732452 | 0.77 | LMNA (0.42) | MMP2CTSCERAP2ERAP1LNPEP | |
| SCHEMBL7723243 | 0.76 | CTSL (0.43) | MMP2CTSCERAP2ERAP1LNPEP | |
| SCHEMBL7731860 | 0.76 | FAAH (0.46) | FAAHDAGLACES1CTSL | |
| Trifluoroacetic Acid SCHEMBL7723157 | 0.75 | HPGD (0.39) | MMP2CTSCHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL7734124 | 0.75 | CYP1A2 (0.42) | DAGLAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |