SCHEMBL772938

SCHEMBL772938

NCc1cc(O)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 6/20 0.50
TYR P14679 1/20 0.46
ABAT P80404 1/20 0.44
ENPP2 Q13822 1/20 0.43
LCK P06239 2/20 0.42
HTR2C P28335 1/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
RGS12 O14924 1/20 0.40
CAMKK2 Q96RR4 1/20 0.40
NOX4 Q9NPH5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
BACE1 P56817 1/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 2/20 0.39
HTT P42858 2/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11674225 0.98 EGFR (0.48) EGFRTYRABATENPP2LCK
Hydrochloric Acid SCHEMBL3562527 0.98 EGFR (0.48) EGFRTYRABATENPP2LCK
SCHEMBL1044776 0.81 RECQL (0.58) EGFRTYRLCKHTR2CALDH1A1
SCHEMBL633312 0.80 TYR (0.65) TYRABATMAPTTDP1HTT
SCHEMBL30255614 0.80 TYR (0.65) TYRABATMAPTTDP1HTT
Bromide SCHEMBL10939970 0.79 RECQL (0.56) EGFRTYRLCKHTR2CALDH1A1
SCHEMBL50932 0.79 MAPT (0.58) EGFRTYRLCKALDH1A1MAPT
SCHEMBL10012940 0.79 TYR (0.64) EGFRTYRLCKALDH1A1TP53
SCHEMBL31244463 0.79 MAPT (0.58) EGFRTYRLCKALDH1A1MAPT
SCHEMBL22499985 0.78 BACE1 (0.52) ABATENPP2ALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220112156-A1 ADAMANTANECARBOXYLIC ACID BENZYL AMIDE DERIVATIVE COMPOUND AND SKIN WHITENING COMPOSITION COMPRISING SAME AMOREPACIFIC CORPORATION (KR) 2022-04-14 US claimed
CN-113286779-A Adamantane carboxylic acid benzylamide derivative compound and skin whitening composition containing same 株式会社爱茉莉太平洋 2021-08-20 CN claimed
WO-2020141927-A1 ADAMANTANECARBOXYLIC ACID BENZYL AMIDE DERIVATIVE COMPOUND AND SKIN WHITENING COMPOSITION COMPRISING SAME ㈜아모레퍼시픽 2020-07-09 WO claimed
EP-0641311-A1 NOVEL DIHYDROXYBENZYLAMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Aventis Pharma S.A. (FR) 1995-03-08 EP claimed
WO-1993023364-A1 NOVEL DIHYDROXYBENZYLAMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME RHONE-POULENC RORER S.A. (FR) 1993-11-25 WO claimed
US-12017974-B2 Adamantanecarboxylic acid benzyl amide derivative compound and skin whitening composition comprising same AMOREPACIFIC CORPORATION (KR) 2024-06-25 US disclosed
US-20240068988-A1 SYSTEMS AND METHODS FOR RAPID PATHOGEN DETECTION MARSHALL DARRELL D (US) 2024-02-29 US disclosed
US-20230364032-A1 USE OF 2-HOBA TO TREAT ATHEROSCLEROSIS VANDERBILT UNIVERSITY 2023-11-16 US disclosed
US-20230355549-A1 METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS VANDERBILT UNIVERSITY 2023-11-09 US disclosed
US-20230330049-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER MTI BIOTECH, INC. 2023-10-19 US disclosed
US-11696903-B2 Compounds and methods for scavenging dicarbonyl electrophiles VANDERBILT UNIVERSITY (US) 2023-07-11 US disclosed
US-20230181494-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER MTI BIOTECH, INC. 2023-06-15 US disclosed
US-4387154-A SPACED MICROVESSELS HAVING A SURFACE OPENING FILLED WITH PHOTOSENSITI MATERIAL; ANTIHALATION AGENTS; SUPPRESSION OF IMAGE SPREADING; X-RAY COLOR; BLACK AND WHITE FILMS EASTMAN KODAK COMPANY (US) 1983-06-07 US disclosed
US-4375507-A Imaging with nonplanar support multicolor filter elements EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4367279-A Silver halide complexing agents of sulfones, nitriles, and onium salts EASTMAN KODAK COMPANY (US) 1983-01-04 US disclosed
US-4362806-A PHOTOGRAPHY, SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1982-12-07 US disclosed
US-4228230-A Ultrasonic imaging of internally fogged silver halide elements EASTMAN KODAK COMPANY (US) 1980-10-14 US disclosed
EP-0013652-A2 Ultrasonographic process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-23 EP disclosed
US-4139379-A Photographic elements containing ballasted electron-accepting nucleophilic displacement compounds EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-4065435-A OXIDATION-REDUCTION PROPERTIES, ACRYLIC FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12017974-B2 Adamantanecarboxylic acid benzyl amide derivative compound and skin whitening composition comprising same TYR, DDC, AANAT EGFR 2449/4885TYR 1/4885ABAT 495/4885
US-20230181494-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER CPT1A, AKR7A2, FABP1 EGFR 4791/4885TYR 2039/4885ABAT 69/4885
US-20230364032-A1 USE OF 2-HOBA TO TREAT ATHEROSCLEROSIS HACL2, APOB, OAT EGFR 3309/4885TYR 1786/4885ABAT 572/4885
US-20230355549-A1 METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS FABP2, SI, MLN EGFR 2948/4885TYR 2399/4885ABAT 1684/4885
US-20230330049-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER GGT1, GGH, AKR7A2 EGFR 4789/4885TYR 2388/4885ABAT 330/4885
US-20220112156-A1 ADAMANTANECARBOXYLIC ACID BENZYL AMIDE DERIVATIVE COMPOUND AND SKIN WHITENING COMPOSITION COMPRISING SAME TYR, DDC, AANAT EGFR 2449/4885TYR 1/4885ABAT 495/4885
US-11696903-B2 Compounds and methods for scavenging dicarbonyl electrophiles OGG1, LGMN, GLO1 EGFR 4853/4885TYR 1161/4885ABAT 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.