Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731113 | 0.91 | PRSS8 (0.34) | XDHLNPEPHDAC1HDAC8ERAP2 | |
| SCHEMBL7732041 | 0.90 | CTSL (0.39) | LNPEPERAP2ERAP1NPC1RAB9A | |
| SCHEMBL7734185 | 0.89 | LNPEP (0.34) | LNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.87 | LMNA (0.39) | LMNAKMT2ACETPMASP2F2 | |
| SCHEMBL7732452 | 0.85 | LMNA (0.42) | LMNAKMT2ACETPMASP2F2 | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.77 | MMP2 (0.38) | LNPEPHDAC1HDAC8ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.77 | CTSL (0.41) | LNPEPERAP2ERAP1NPC1RAB9A | |
| SCHEMBL7723159 | 0.77 | HDAC3 (0.35) | LNPEPHDAC1HDAC8 | |
| SCHEMBL7734127 | 0.77 | CYP3A4 (0.38) | LMNAKMT2ALNPEPHDAC1HDAC8 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.76 | OPRK1 (0.37) | LNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |