Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7735796 | 0.88 | HRH2 (0.34) | METAP2METAP1F9ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.82 | OPRK1 (0.37) | METAP2METAP1ERAP2ERAP1LNPEP | |
| SCHEMBL7734185 | 0.81 | LNPEP (0.34) | ERAP2ERAP1LNPEP | |
| SCHEMBL7730106 | 0.79 | CTSC (0.38) | METAP2METAP1ERAP2ERAP1LNPEP | |
| SCHEMBL7734187 | 0.76 | F9 (0.30) | METAP2METAP1F9 | |
| SCHEMBL7729637 | 0.73 | METAP2 (0.41) | METAP2METAP1ERAP2ERAP1TP53 | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.72 | MMP2 (0.38) | ERAP2ERAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.72 | CTSL (0.41) | ERAP2ERAP1LNPEP | |
| SCHEMBL7734143 | 0.72 | ATM (0.46) | — | |
| SCHEMBL7731093 | 0.71 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |