Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731113 | 0.91 | PRSS8 (0.34) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL7732041 | 0.90 | CTSL (0.39) | LNPEPERAP2ERAP1MMP2CHRNB2 | |
| SCHEMBL7733848 | 0.89 | LMNA (0.38) | LNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.87 | OPRK1 (0.37) | LNPEPERAP2ERAP1MMP2CTSC | |
| SCHEMBL7730106 | 0.84 | CTSC (0.38) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL7735797 | 0.81 | METAP2 (0.32) | LNPEPERAP2ERAP1 | |
| SCHEMBL7723159 | 0.78 | HDAC3 (0.35) | LNPEPMMP2LTA4HCTSC | |
| SCHEMBL7734127 | 0.78 | CYP3A4 (0.38) | LNPEPERAP2ERAP1MMP2LTA4H | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.77 | MMP2 (0.38) | LNPEPERAP2ERAP1MMP2LTA4H | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.76 | CTSL (0.41) | LNPEPERAP2ERAP1MMP2CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |